Evidence map›Paper›PMID 33867032›Full record

ArticleAnalytica chimica acta2021

First electrochemical evaluation of favipiravir used as an antiviral option in the treatment of COVID-19: A study of its enhanced voltammetric determination in cationic surfactant media using a boron-doped diamond electrode.

Shabnam Allahverdiyeva, Oruc Yunusoğlu, Yavuz Yardım, Zühre Şentürk

Open access · greenAbstract read
In one paragraph

Article in Analytica chimica acta, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 98 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Shabnam AllahverdiyevaVan Yuzuncu Yil University, Faculty of Science, Department of Biochemistry, 65080, Van, Turkey.
Oruc YunusoğluVan Yuzuncu Yil University, Faculty of Medicine, Department of Pharmacology, 65080, Van, Turkey.
Yavuz YardımVan Yuzuncu Yil University, Faculty of Pharmacy, Department of Analytical Chemistry, 65080, Van, Turkey. Electronic address: yavuzyardim2002@yahoo.com.
Zühre ŞentürkVan Yuzuncu Yil University, Faculty of Science, Department of Analytical Chemistry, 65080, Van, Turkey. Electronic address: zuhresenturk@hotmail.com.
Van Yüzüncü Yıl Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Favipiravir, a promising antiviral agent, is undergoing clinical trials for the potential treatment of the novel coronavirus disease 2019 (COVID-19). This is the first report for the electrochemical activity of favipiravir and its electroanalytical sensing. For this purpose, the effect of cationic surfactant, CTAB was demonstrated on the enhanced accumulation of favipiravir at the surface of cathodically pretreated boron-doped diamond (CPT-BDD) electrode. At first, the electrochemical properties of favipiravir were investigated in the surfactant-free solutions by the means of cyclic voltammetry. The compound presented a single oxidation step which is irreversible and adsorption controlled. A systematic study of various operational conditions, such as electrode pretreatment, pH of the supporting electrolyte, concentration of CTAB, accumulation variables, and instrumental parameters on the adsorptive stripping response, was examined using square-wave voltammetry. An oxidation signal at around +1.21 V in Britton-Robinson buffer at pH 8.0 containing 6 × 10

Indexed as

BoronDiamondElectrodesAmidesAntiviral AgentsHumansPyrazinesSARS-CoV-2Surface-Active AgentsAmidesAntiviral AgentsBoronDiamondfavipiravirPyrazinesSurface-Active AgentsCathodically pretreated boron-doped diamondCetyltrimethylammonium bromideFavipiravirReal samplesSquare-wave adsorptive stripping voltammetry

Identifiers

PMID33867032
PMCPMC7971419
OpenAlexW3137790395

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.