Evidence map›Paper›PMID 33866797›Full record

ArticleHypertension (Dallas, Tex. : 1979)2021

Contributions of Cerebral Blood Flow to Associations Between Blood Pressure Levels and Cognition: The Age, Gene/Environment Susceptibility-Reykjavik Study.

Justine E Moonen, Behnam Sabayan, Sigurdur Sigurdsson, Mark A van Buchem, Vilmundur Gudnason, Osorio Meirelles, Lenore J Launer

Open access · bronzeAbstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Peripheral risk factors and their role in biomarker-based screening for dementia in the community.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  5. Article
  6. Article
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  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Justine E MoonenFrom the Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, National Institute of Health, Baltimore, MD (J.E.M., O.M., L.J.L.).
Behnam SabayanDepartment of Neurology, Feinberg School of Medicine, Northwestern University, Massachusetts General Hospital, Harvard Medical School, Boston (B.S.).
Sigurdur SigurdssonIcelandic Heart Association Research Institute, Kópavogur, Iceland (S.S., V.G.).
Mark A van BuchemDepartment of Radiology, Leiden University Medical Center, the Netherlands (M.A.v.B.).
Vilmundur GudnasonIcelandic Heart Association Research Institute, Kópavogur, Iceland (S.S., V.G.).
Osorio MeirellesFrom the Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, National Institute of Health, Baltimore, MD (J.E.M., O.M., L.J.L.).
Lenore J LaunerFrom the Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, National Institute of Health, Baltimore, MD (J.E.M., O.M., L.J.L.).
National Institute on Aging · USIcelandic Heart Association · ISLeiden University Medical Center · NLNorthwestern University · USUniversity of Iceland · IS

Funding

Brain aging and cardiovascular risk factors and diseaseZIAAG007480 · NIA · NATIONAL INSTITUTE ON AGING · PI LAUNER, LENORE J · 2011 to 2025
$2.7M
Intramural NIH HHS ZIA AG007480
6 · The paper itself

Abstract

[Figure: see text].

Indexed as

AgedAged, 80 and overAge FactorsBlood PressureBrainCerebrovascular CirculationCognitionFemaleGene-Environment InteractionGenetic Predisposition to DiseaseHumansIcelandMagnetic Resonance ImagingMaleaged blood pressurecerebral blood flow cognitiondementia

Identifiers

PMID33866797
PMCPMC8119347
OpenAlexW3154242648

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.