Evidence map›Paper›PMID 33866785›Full record

ArticleJournal of proteome research2021

Heterogeneity of Lipid and Protein Cartilage Profiles Associated with Human Osteoarthritis with or without Type 2 Diabetes Mellitus.

Maxime R Eveque-Mourroux, Pieter J Emans, Annelies Boonen, Britt S R Claes, Freek G Bouwman, Ron M A Heeren, Berta Cillero-Pastor

Open access · greenAbstract read
In one paragraph

Article in Journal of proteome research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Maxime R Eveque-MourrouxDivision of Imaging Mass Spectrometry, Maastricht MultiModal Molecular Imaging (M4i) Institute, 6229 ER Maastricht, Netherlands.
Pieter J EmansDepartment of Orthopedic Surgery, Maastricht University Medical Center, 6229 HX Maastricht, Netherlands.
Annelies BoonenDepartment of Internal Medicine, Division of Rheumatology, and Care and Public Health Research Institute (CAPHRI), Maastricht University Medical Center, 6229 HX Maastricht, Netherlands.
Britt S R ClaesDivision of Imaging Mass Spectrometry, Maastricht MultiModal Molecular Imaging (M4i) Institute, 6229 ER Maastricht, Netherlands.
Freek G BouwmanDepartment of Human Biology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, 6229 HX Maastricht, Netherlands.
Ron M A HeerenDivision of Imaging Mass Spectrometry, Maastricht MultiModal Molecular Imaging (M4i) Institute, 6229 ER Maastricht, Netherlands.ORCID 0000-0002-6533-7179
Berta Cillero-PastorDivision of Imaging Mass Spectrometry, Maastricht MultiModal Molecular Imaging (M4i) Institute, 6229 ER Maastricht, Netherlands.ORCID 0000-0002-7407-1165
Maastricht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoarthritis (OA) is a multifactorial pathology and comprises a wide range of distinct phenotypes. In this context, the characterization of the different molecular profiles associated with each phenotype can improve the classification of OA. In particular, OA can coexist with type 2 diabetes mellitus (T2DM). This study investigates lipidomic and proteomic differences between human OA/T2DM

Indexed as

Cartilage, ArticularDiabetes Mellitus, Type 2OsteoarthritisHumansLipidsProteomicsSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationLipidscartilagediabeteslabel-free proteomicsMALDI-MSIosteoarthritisspatially resolved-lipid analysis

Identifiers

PMID33866785
PMCPMC8155553
OpenAlexW3154672129

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.