Evidence map›Paper›PMID 33866467›Full record

ArticleThe international journal of cardiovascular imaging2021

Feasibility of semi-recumbent bicycle exercise Doppler echocardiography for the evaluation of the right heart and pulmonary circulation unit in different clinical conditions: the RIGHT heart international NETwork (RIGHT-NET).

Francesco Ferrara, Luna Gargani, Robert Naeije, Lawrence Rudski, William F Armstrong, Karina Wierzbowska-Drabik, Paola Argiento, Francesco Bandera, Filippo Cademartiri, Rodolfo Citro and 21 more

Abstract read
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In one paragraph

Article in The international journal of cardiovascular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Exercise Pulmonary Hypertension in Heart Valve Disease.Reviews in cardiovascular medicine · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Training, training and more training.The international journal of cardiovascular imaging · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors at 17 institutions in 6 countries.

Francesco FerraraCardio-Thoracic-Vascular Department, University Hospital "San Giovanni Di Dio E Ruggi D'Aragona", Salerno, Italy.
Luna GarganiInstitute of Clinical Physiology - C.N.R, Pisa, Italy.
Robert NaeijeFree University of Brussels, Brussels, Belgium.
Lawrence RudskiAzrieli Heart Center and Center for Pulmonary Vascular Diseases, Jewish General Hospital, McGill University, Montreal, QC, Canada.
William F ArmstrongDivision of Cardiovascular Medicine, University of Michigan Medical Center, Ann Arbor, MI, USA.
Karina Wierzbowska-DrabikI Department and Chair of Cardiology, Bieganski Hospital, Medical University of Lodz, Lodz, Poland.
Paola ArgientoDepartment of Cardiology, University of Campania "Luigi Vanvitelli", Naples, Italy.
Francesco BanderaHeart Failure Unit and Cardiopulmonary Laboratory, IRCCS Policlinico San Donato University Hospital, Milan, Italy.
Filippo CademartiriIRCCS SDN, Naples, Italy.
Rodolfo CitroCardio-Thoracic-Vascular Department, University Hospital "San Giovanni Di Dio E Ruggi D'Aragona", Salerno, Italy.
Antonio CittadiniDepartment of Translational Medical Sciences, Federico II University, Naples, Italy.
Rosangela CocchiaCardiology Division, A Cardarelli Hospital, Naples, Italy.
Carla ContaldiCardio-Thoracic-Vascular Department, University Hospital "San Giovanni Di Dio E Ruggi D'Aragona", Salerno, Italy.
Michele D'AltoDepartment of Cardiology, University of Campania "Luigi Vanvitelli", Naples, Italy.
Antonello D'AndreaDepartment of Cardiology, Umberto I Hospital Nocera Inferiore, Nocera Inferiore, Italy.
Ekkehard GrünigDivision of Cardiovascular Medicine, University of Michigan Medical Center, Ann Arbor, MI, USA.
Marco GuazziHeart Failure Unit and Cardiopulmonary Laboratory, IRCCS Policlinico San Donato University Hospital, Milan, Italy.
Theodore John KoliasDivision of Cardiovascular Medicine, University of Michigan Medical Center, Ann Arbor, MI, USA.
Giuseppe LimongelliDepartment of Cardiology, University of Campania "Luigi Vanvitelli", Naples, Italy.
Alberto Maria MarraDepartment of Translational Medical Sciences, Federico II University, Naples, Italy.
Ciro MauroCardiology Division, A Cardarelli Hospital, Naples, Italy.
Antonella MoreoA. De Gasperis Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Brigida RanieriIRCCS SDN, Naples, Italy.
Rajan SaggarLung & Heart-Lung Transplant and Pulmonary Hypertension Programs, David Geffen School of Medicine, UCLA, Los Angeles, USA.
Andrea SalzanoDepartment of Translational Medical Sciences, Federico II University, Naples, Italy.
Anna Agnese StanziolaDepartment of Respiratory Diseases, Monaldi Hospital, University "Federico II", Naples, Italy.
Olga VrizHeart Centre, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Mani VannanPiedmont Heart Institute, Marcus Heart Valve Center, Atlanta, USA.
Jaroslaw D KasprzakI Department and Chair of Cardiology, Bieganski Hospital, Medical University of Lodz, Lodz, Poland.
Eduardo Bossone *Cardiology Division, A Cardarelli Hospital, Naples, Italy. ebossone@hotmail.com.ORCID http://orcid.org/0000-0003-2769-9950
RIGHT Heart International NETwork (RIGHT-NET)
Federico II University Hospital · ITUniversity of Milan · ITUniversity of Campania "Luigi Vanvitelli" · ITOspedali Riuniti San Giovanni di Dio e Ruggi d'Aragona · ITMedical University of Lodz · PLSDN Istituto di Ricerca Diagnostica e Nucleare · ITUniversity of Michigan · USIstituto di Fisiologia Clinica · ITUniversity of California, Los Angeles · USAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITHeidelberg University · DEOspedale Antonio Cardarelli · ITValve (United States) · USKing Faisal Specialist Hospital & Research Centre · SAOspedale Monaldi · ITPoliclinico Umberto I · ITJewish General Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exercise Doppler echocardiography (EDE) is a well-validated tool in ischemic and valvular heart diseases. However, its use in the assessment of the right heart and pulmonary circulation unit (RH-PCU) is limited. The aim of this study is to assess the semi-recumbent bicycle EDE feasibility for the evaluation of RH-PCU in a large multi-center population, from healthy individuals and elite athletes to patients with overt or at risk of developing pulmonary hypertension (PH). From January 2019 to July 2019, 954 subjects [mean age 54.2 ± 16.4 years, range 16-96, 430 women] underwent standardized semi-recumbent bicycle EDE with an incremental workload of 25 watts every 2 min, were prospectively enrolled among 7 centers participating to the RIGHT Heart International NETwork (RIGHT-NET). EDE parameters of right heart structure, function and pressures were obtained according to current recommendations. Right ventricular (RV) function at peak exercise was feasible in 903/940 (96%) by tricuspid annular plane systolic excursion (TAPSE), 667/751 (89%) by tissue Doppler-derived tricuspid lateral annular systolic velocity (S') and 445/672 (66.2%) by right ventricular fractional area change (RVFAC). RV-right atrial pressure gradient [RV-RA gradient = 4 × tricuspid regurgitation velocity

Indexed as

Pulmonary CirculationVentricular Dysfunction, RightAdolescentAdultAgedAged, 80 and overBicyclingEchocardiography, DopplerFeasibility StudiesFemaleHumansMiddle AgedPredictive Value of TestsVentricular Function, RightYoung AdultExercise Doppler echocardiographyPulmonary circulationPulmonary hypertensionRight heartRight ventricle

Identifiers

PMID33866467
OpenAlexW3152855634

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.