ArticleSurgery today2021
Preoperative serum cholinesterase levels as a risk factor of postoperative complications for the elderly undergoing emergency surgery.
Article in Surgery today, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 10 citations in OpenAlex.
- Development, internal testing, and external validation of an interpretable machine-learning model for predicting imaging-confirmed in-hospital postoperative deep vein thrombosis in older patients with patellar fractures.BMC medical informatics and decision making · 2026Article
- Preoperative butyrylcholinesterase activity and risk of postoperative delirium: A meta-analysis.World journal of psychiatry · 2026Article
- Low Cholinesterase Is a Potential Poor Prognostic Factor in Colorectal Cancer Presenting With Tumor Markers Negative.Cancer reports (Hoboken, N.J.) · 2025Article
- Risk Prediction of Postoperative Complications in Lower Gastrointestinal Perforation Based on Preoperative Serum Cholinesterase Levels.Journal of the anus, rectum and colon · 2025Article
- Consensus-based recommendations for optimizing perioperative nutritional support and muscle health in major surgery in India.Frontiers in nutrition · 2025Article
- Article
- The influence of serum cholinesterase levels and sarcopenia on postoperative infectious complications in colorectal cancer surgery.Surgery today · 2023Article
- The impact of low serum cholinesterase levels on survival in patients with colorectal cancer.International journal of colorectal disease · 2022Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposesAn accurate assessment of preoperative malnutrition in the elderly is critically important to predicting postoperative complications. The aim of this study is to evaluate the predictive value of the preoperative serum cholinesterase levels as a risk factor for postoperative complications in the elderly who have undergone emergency surgery.
methodsThe study comprised 60 elderly patients who had undergone emergency major gastroenterological surgery. We retrospectively investigated the relationship between the preoperative serum cholinesterase levels and postoperative complications (Clavien-Dindo classification ≥ II). Univariate and multivariate analyses were performed to evaluate the risk factors for postoperative complications.
resultsThirty-three patients (55%) developed postoperative complications. According to the univariate analysis, hemoglobin (P = 0.018), albumin (P = 0.0036), cholinesterase (P < 0.001), C-reactive protein (P = 0.043), prognostic nutritional index (P = 0.0050), the Physiologic and Operative Severity Score for the enUmeration of Mortality and Morbidity (P < 0.001) and operation time (P = 0.042) were identified to be risk factors for postoperative complications. According to the multivariate analysis, low preoperative serum cholinesterase levels were found to be an independent risk factor for postoperative complications (P = 0.029). In the extremely elderly (80-95 years), the cholinesterase-low group had a higher complication rate compared to the cholinesterase-high group (77.8 vs 43.8%, P = 0.028).
conclusionThe preoperative serum cholinesterase levels may be a risk factor for postoperative complications in elderly patients after emergency surgery, thus suggesting the significance of cholinesterase in evaluating the nutritional status.
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