Evidence map›Paper›PMID 33866392›Full record

ArticleSkeletal radiology2021

Subchondral insufficiency fracture of the knee: unicompartmental correlation to meniscal pathology and degree of chondrosis by MRI.

Emad Allam, George Boychev, Samuel Aiyedipe, William Morrison, Johannes B Roedl, Adam D Singer, Felix M Gonzalez

Abstract read
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Article in Skeletal radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Emad AllamDepartment of Radiology, Loyola University Medical Center, Chicago, IL, USA.
George BoychevDepartment of Radiology, Loyola University Medical Center, Chicago, IL, USA.
Samuel AiyedipeRollins School of Public Health, Emory University, Atlanta, GA, USA.
William MorrisonDepartment of Radiology and Imaging Sciences, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Johannes B RoedlDepartment of Radiology and Imaging Sciences, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Adam D SingerDepartment of Radiology and Imaging Sciences Section of Musculoskeletal Imaging, Emory University Hospital, 59 Executive Park South, 4th Floor Suite 4009, Atlanta, GA, 30329, USA.
Felix M GonzalezDepartment of Radiology and Imaging Sciences Section of Musculoskeletal Imaging, Emory University Hospital, 59 Executive Park South, 4th Floor Suite 4009, Atlanta, GA, 30329, USA. felix.m.gonzalez@emory.edu.ORCID http://orcid.org/0000-0002-3214-4813
Emory University Hospital · USLoyola University Medical Center · USThomas Jefferson University Hospital · USEmory University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the relationship between low- and high-grade subchondral insufficiency fracture of the knee (SIFK) and meniscal tear/type/location, severity of meniscal extrusion, grade of chondrosis, and extent of surrounding edema-like marrow signal intensity. MATERIALS AND

methodsOur retrospective study included 219 patients with knee pain and SIFK seen on MRI. SIFK lesions were categorized from grade 1 to 4 with a low grade (1 and 2) vs high grade (3 and 4) distinction. Associations between SIFK grade, location, lesion dimensions, edema-like marrow signal intensity, incidence of meniscal tears/type/location, and chondrosis (grade 0 to grade 4), as well as patients' age and weight, were assessed.

resultsOur analysis consisted of 115 males and 104 females with 17% of the patients showing grade 1 SIFK, 59% grade 2, 16% grade 3, and 8% grade 4. No chondrosis or low-grade chondrosis was mostly present in patients with low-grade SIFK (68.9%), whereas high-grade chondrosis was mostly present in patients with high-grade SIFK lesions (65.4%) (p < 0.01). Further sub-analysis demonstrated that high-grade SIFK was associated with high-grade chondrosis in the same compartment (p < 0.01) but not in the adjacent compartment. There was a significant difference in the extent of edema-like marrow signal intensity between the two groups, with high-grade SIFK more frequently demonstrating severe edema-like marrow signal intensity compared to low-grade SIFK (p < 0.01).

conclusionHigh-grade SIFK lesions are associated with unicompartmental high-grade chondrosis.

Indexed as

Fractures, StressKnee InjuriesFemaleHumansKnee JointMagnetic Resonance ImagingMaleMenisci, TibialRetrospective StudiesBone marrow edemaChondrosisInsufficiency fracture of the kneeMeniscusSpontaneous osteonecrosis of the kneeStress fracture of the knee

Identifiers

PMID33866392
OpenAlexW3153465602

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.