Evidence map›Paper›PMID 33866376›Full record

ArticleJournal of radiation research2021

Modified Glasgow Prognostic Score is predictive of prognosis for non-small cell lung cancer patients treated with stereotactic body radiation therapy: a retrospective study.

Zhe Chen, Hotaka Nonaka, Hiroshi Onishi, Eiji Nakatani, Yoko Sato, Satoshi Funayama, Hiroaki Watanabe, Takafumi Komiyama, Kengo Kuriyama, Kan Marino and 7 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal of radiation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Review
  5. Prognostic Value of Inflammation and Nutrition-Based Scores in Non-Small Cell Lung Cancer.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 1 country.

Zhe ChenDepartment of Radiology, School of Medicine, University of Yamanashi, Chuo, Yamanashi, 409-3898, Japan.
Hotaka NonakaDepartment of Radiology, Fuji City General Hospital, Fuji, Shizuoka, 417-8567, Japan.
Hiroshi OnishiDepartment of Radiology, School of Medicine, University of Yamanashi, Chuo, Yamanashi, 409-3898, Japan.
Eiji NakataniDivision of Statistical Analysis, Research Support Center, Shizuoka General Hospital, Shizuoka, Shizuoka, 420-8527, Japan.
Yoko SatoDivision of Statistical Analysis, Research Support Center, Shizuoka General Hospital, Shizuoka, Shizuoka, 420-8527, Japan.
Satoshi FunayamaDepartment of Radiology, School of Medicine, University of Yamanashi, Chuo, Yamanashi, 409-3898, Japan.
Hiroaki WatanabeDepartment of Radiology, School of Medicine, University of Yamanashi, Chuo, Yamanashi, 409-3898, Japan.
Takafumi KomiyamaDepartment of Radiology, School of Medicine, University of Yamanashi, Chuo, Yamanashi, 409-3898, Japan.
Kengo KuriyamaDepartment of Radiology, Shizuoka General Hospital, Shizuoka, Shizuoka, 420-8527, Japan.
Kan MarinoDepartment of Radiology, School of Medicine, University of Yamanashi, Chuo, Yamanashi, 409-3898, Japan.
Shinichi AokiDepartment of Radiology, School of Medicine, University of Yamanashi, Chuo, Yamanashi, 409-3898, Japan.
Masayuki ArayaProton Therapy Center, Aizawa Hospital, Matsumoto, Nagano, 390-8510, Japan.
Licht TominagaDepartment of Radiology, Toranomon Hospital, Minato, Tokyo, 105-8470, Japan.
Ryo SaitoDepartment of Radiology, Shimada Municipal Hospital, Shimada, Shizuoka, 427-8502, Japan.
Yoshiyasu MaehataDepartment of Radiology, School of Medicine, University of Yamanashi, Chuo, Yamanashi, 409-3898, Japan.
Mitsuhiko OguriDepartment of Radiology, Yamanashi Prefectural Hospital, Yamanashi, Yamanashi, 400-8506, Japan.
Masahide SaitoDepartment of Radiology, School of Medicine, University of Yamanashi, Chuo, Yamanashi, 409-3898, Japan.
University of Yamanashi · JPShizuoka General Hospital · JPAizawa Hospital · JPFujieda Municipal General Hospital · JPShimada Municipal Hospital · JPToranomon Hospital · JPYamanashi Prefectural Central Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to assess the predictive value of the modified Glasgow prognostic score (mGPS) in patients with non-small cell lung cancer (NSCLC) who underwent stereotactic body radiation therapy (SBRT). We retrospectively reviewed the records of 207 patients, with a median age of 79 years. The pretreatment mGPS was calculated and categorized as high (mGPS = 1-2) or low (mGPS = 0). The median follow-up duration was 40.7 months. The five-year overall survival (OS), progression-free survival (PFS) and time to progression (TTP) rates were 44.3%, 36% and 54.4%, respectively. Multivariate analysis revealed that mGPS was independently predictive of OS (hazard ratio [HR] 1.67; 95% confidence interval 1.14-2.44: P = 0.009), PFS (HR 1.58; 1.10-2.28: P = 0.014) and TTP (HR 1.66; 1.03-2.68: P = 0.039). Patients who had high mGPS showed significantly worse OS (33.3 vs 64.5 months, P = 0.003) and worse PFS (23.8 vs 39 months, P = 0.008) than those who had low mGPS. The data showed a trend that patients with high mGPS suffered earlier progression compared to those with low mGPS (54.3 vs 88.1 months, P = 0.149). We confirmed that mGPS is independently predictive of prognosis in NSCLC patients treated with SBRT.

Indexed as

RadiosurgeryAgedAged, 80 and overCarcinoma, Non-Small-Cell LungFemaleHumansKaplan-Meier EstimateLung NeoplasmsMaleMiddle AgedMultivariate AnalysisPrognosisProgression-Free SurvivalProportional Hazards ModelsRetrospective Studiesbiological markersmodified Glasgow prognostic score (mGPS)non-small cell lung cancer (NSCLC)prognosisstereotactic body radiation therapy (SBRT)

Identifiers

PMID33866376
PMCPMC8127692
OpenAlexW3154462001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.