Evidence map›Paper›PMID 33866363›Full record

ArticleJournal of radiation research2021

Stereotactic body radiotherapy for kidney cancer: a 10-year experience from a single institute.

Takaya Yamamoto, Yoshihide Kawasaki, Rei Umezawa, Noriyuki Kadoya, Haruo Matsushita, Kazuya Takeda, Yojiro Ishikawa, Noriyoshi Takahashi, Yu Suzuki, Ken Takeda and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of radiation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Takaya YamamotoDepartment of Radiation Oncology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Yoshihide KawasakiDepartment of Urology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Rei UmezawaDepartment of Radiation Oncology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Noriyuki KadoyaDepartment of Radiation Oncology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Haruo MatsushitaDepartment of Radiation Oncology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Kazuya TakedaDepartment of Radiation Oncology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Yojiro IshikawaDepartment of Radiation Oncology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Noriyoshi TakahashiDepartment of Radiation Oncology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Yu SuzukiDepartment of Radiation Oncology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Ken TakedaDepartment of Radiation Oncology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Kousei KawabataDepartment of Radiation Oncology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Akihiro ItoDepartment of Urology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Keiichi JinguDepartment of Radiation Oncology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Tohoku University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this retrospective study was to investigate survival outcomes and irradiated tumor control (local control [LC]) and locoregional control (LRC) after stereotactic body radiotherapy (SBRT) for T1 or recurrent T1 (rT1) kidney cancer. Twenty-nine nonconsecutive patients with 30 tumors were included. SBRT doses of 70 Gy, 60 Gy or 50 Gy in 10 fractions were prescribed with a linear accelerator using daily image guidance. The Kaplan-Meier method was used to estimate time-to-event outcomes, and the log-rank test was used to compare survival curves between groups divided by each possible factor. The median follow-up periods for all patients and survivors were 57 months and 69.6 months, respectively. The five-year LC rate, LRC rate, progression-free survival (PFS) rate, disease-specific survival (DSS) rate and overall survival (OS) rate were 94%, 88%, 50%, 96% and 68%, respectively. No significant factor was related to OS and PFS. Three of 24 non-hemodialysis (HD) patients had new-onset-HD because of the progression of underlying kidney disease. Grade 3 or higher toxicities from SBRT did not occur. In conclusion, SBRT for kidney cancer provided a high rate of LC, LRC and DSS with minimal toxicities, but patient selection and indication for SBRT should be done carefully considering the relatively low OS rate.

Indexed as

RadiosurgeryDisease-Free SurvivalDose-Response Relationship, RadiationFemaleFollow-Up StudiesHumansKaplan-Meier EstimateKidney NeoplasmsMaleTomography, X-Ray Computedkidney cancerlocal control (LC)renal cell carcinomastereotactic body radiotherapy (SBRT)

Identifiers

PMID33866363
PMCPMC8127673
OpenAlexW3153182086

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.