ArticleCerebral cortex (New York, N.Y. : 1991)2021
Cortical Networks Underpinning Compensation of Verbal Fluency in Normal Aging.
Article in Cerebral cortex (New York, N.Y. : 1991), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Preserved topography, lateralization, selectivity, and functional connectivity of the language network in older brains.Nature communications · 2026Article
- The cognitive connectome in dementia with lewy bodies undergoes early alterations already at the mild cognitive impairment stage.Scientific reports · 2025Article
- Patients with dementia with Lewy bodies display a signature alteration of their cognitive connectome.Scientific reports · 2025Article
- The effect of chess on cognition: a graph theory study on cognitive data.Frontiers in psychology · 2024Article
- Contribution of White Matter Fiber Bundle Damage to Language Change After Surgery for Temporal Lobe Epilepsy.Neurology · 2023Article
- Age-related reorganization of functional network architecture in semantic cognition.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- [The measurements of the similarity of dynamic brain functional network].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2022Article
- Lesion correlates of auditory sentence comprehension deficits in post-stroke aphasia.Neuroimage. Reports · 2022Article
- Functional topologies of spatial cognition predict cognitive and motor progression in Parkinson's.Frontiers in aging neuroscience · 2022Article
- Engagement of Language and Domain General Networks during Word Monitoring in a Native and Unknown Language.Brain sciences · 2021Article
- Cognitive dedifferentiation as a function of cognitive impairment in the ADNI and MemClin cohorts.Aging · 2021Article
- The Cognitive Connectome in Healthy Aging.Frontiers in aging neuroscience · 2021Article
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Authors and funding
6 authors.
Funding
Abstract
Elucidating compensatory mechanisms underpinning phonemic fluency (PF) may help to minimize its decline due to normal aging or neurodegenerative diseases. We investigated cortical brain networks potentially underpinning compensation of age-related differences in PF. Using graph theory, we constructed networks from measures of thickness for PF, semantic, and executive-visuospatial cortical networks. A total of 267 cognitively healthy individuals were divided into younger age (YA, 38-58 years) and older age (OA, 59-79 years) groups with low performance (LP) and high performance (HP) in PF: YA-LP, YA-HP, OA-LP, OA-HP. We found that the same pattern of reduced efficiency and increased transitivity was associated with both HP (compensation) and OA (aberrant network organization) in the PF and semantic cortical networks. When compared with the OA-LP group, the higher PF performance in the OA-HP group was associated with more segregated PF and semantic cortical networks, greater participation of frontal nodes, and stronger correlations within the PF cortical network. We conclude that more segregated cortical networks with strong involvement of frontal nodes seemed to allow older adults to maintain their high PF performance. Nodal analyses and measures of strength were helpful to disentangle compensation from the aberrant network organization associated with OA.
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