ArticleTranslational psychiatry2021
Altered relationship between subjective perception and central representation of touch hedonics in adolescents with autism-spectrum disorder.
Article in Translational psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- The role of affective touch in mental illness: a systematic review of CT fiber dysregulation in psychological disorders and the therapeutic potential of CT fiber stimulation.Frontiers in psychiatry · 2025Pooled it
- Article
- Brain-body interactions in systemic diseases: a survey from an imaging perspective.MedScience · 2026Review
- Through Massage to the Brain-Neuronal and Neuroplastic Mechanisms of Massage Based on Various Neuroimaging Techniques (EEG, fMRI, and fNIRS).Journal of clinical medicine · 2026Review
- Can you feel it? Altered affective touch perception in a transdiagnostic sample of female adolescents with nonsuicidal self-injury.Translational psychiatry · 2025Article
- Centrality of Touch Avoidance in Social Touch Experiences in Autism.Journal of autism and developmental disorders · 2025Article
- Primary sensory neuron dysfunction underlying mechanical itch hypersensitivity in a Shank3 mouse model of autism.Translational psychiatry · 2025Article
- Rapid and Unpredictable Shifts in Perceived Pleasantness of Continuous Affective Touch.Behavioral sciences (Basel, Switzerland) · 2025Article
- The Proximity Prediction Hypothesis: How predictive coding of CT-touch explains Autonomous Sensory Meridian Response and its therapeutic applications.Frontiers in behavioral neuroscience · 2025Article
- Article
- Research Progress on Neural Processing of Hand and Forearm Tactile Sensation: A Review Based on fMRI Research.Neuropsychiatric disease and treatment · 2025Review
- Untouched: understanding the role of touch in obsessive-compulsive disorder.Frontiers in psychiatry · 2025Review
- MDMA modulates human sensorimotor cortical pathways during gentle touch.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Autistic Traits Related to the Importance of Interpersonal Touch and Appreciation of Observed Touch during COVID-19 Social Distancing.International journal of environmental research and public health · 2023Article
- Social Touch: Its Mirror-like Responses and Implications in Neurological and Psychiatric Diseases.NeuroSci · 2023Review
- The perception of affective touch in women affected by obesity.Frontiers in psychology · 2023Article
- Article
- Therapeutic touch and therapeutic alliance in pediatric care and neonatology: An active inference framework.Frontiers in pediatrics · 2023Article
- Atypical Response to Affective Touch in Children with Autism: Multi-Parametric Exploration of the Autonomic System.Journal of clinical medicine · 2022Article
- Tactile Biography Questionnaire: A contribution to its validation in an Italian sample.PloS one · 2022Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An impairment of social communication is a core symptom of autism-spectrum disorder (ASD). Affective touch is an important means of social interaction, and C-Tactile (CT) afferents are thought to play a key role in the peripheral detection and encoding of these stimuli. Exploring the neural and behavioral mechanisms for processing CT-optimal touch (~3 cm/s) may therefore provide useful insights into the pathophysiology of ASD. We examined the relationship between touch hedonics (i.e. the subjective pleasantness with which affective touch stimuli are perceived) and neural processing in the posterior superior temporal sulcus (pSTS). This region is less activated to affective touch in individuals with ASD, and, in typically developing individuals (TD), is correlated positively with touch pleasantness. TD and ASD participants received brushing stimuli at CT-optimal, and CT-non-optimal speeds during fMRI. Touch pleasantness and intensity ratings were collected, and affective touch awareness, a measure of general touch hedonics was calculated. As expected, slow touch was perceived as more pleasant and less intense than fast touch in both groups, whereas affective touch awareness was moderately higher in TD compared to ASD. There was a strong, positive correlation between right pSTS activation and affective touch awareness in TD, but not in ASD. Our findings suggest that altered neural coupling between right pSTS and touch hedonics in ASD may be associated with social touch avoidance in ASD.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.