Evidence map›Paper›PMID 33865858›Full record

ArticleThe Journal of biological chemistry

The Escherichia coli S2P intramembrane protease RseP regulates ferric citrate uptake by cleaving the sigma factor regulator FecR.

Tatsuhiko Yokoyama, Tomoya Niinae, Kazuya Tsumagari, Koshi Imami, Yasushi Ishihama, Yohei Hizukuri, Yoshinori Akiyama

Open access · goldAbstract read
In one paragraph

Article in The Journal of biological chemistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Phage lysis protein LysScience advances · 2025
    Article
  7. Evidence for a Putative Regulatory System Consisting of an ECF σInternational journal of molecular sciences · 2025
    Article
  8. Article
  9. Review
  10. Cleavage cascade of the sigma regulator FecR orchestrates TonB-dependent signal transduction.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Increased Amino Acid Absorption Mediated byJournal of microbiology and biotechnology · 2023
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Tatsuhiko YokoyamaInstitute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan.
Tomoya NiinaeGraduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan.
Kazuya TsumagariGraduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan.
Koshi ImamiGraduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan.
Yasushi IshihamaGraduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan.
Yohei HizukuriInstitute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan. Electronic address: yhizukur@infront.kyoto-u.ac.jp.
Yoshinori AkiyamaInstitute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan. Electronic address: yakiyama@infront.kyoto-u.ac.jp.
Kyoto University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Escherichia coli RseP, a member of the site-2 protease family of intramembrane proteases, is involved in the activation of the σ

Indexed as

Gene Expression Regulation, BacterialBiological TransportCell MembraneEndopeptidasesEscherichia coliEscherichia coli ProteinsFerric CompoundsMembrane ProteinsMembrane Transport ProteinsSigma FactorEndopeptidasesEscherichia coli ProteinsFecR protein, E coliferric citrateFerric CompoundsMembrane ProteinsMembrane Transport ProteinsRseP protein, E coliSigma Factorbacterial signal transductionintramembrane-cleaving proteasesiron uptakemetal homeostasismetalloproteasemultistep processingproteomicsregulated intramembrane proteolysissiderophoresite-2 protease

Identifiers

PMID33865858
PMCPMC8144685
OpenAlexW3153941843

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.