ReviewChest2021
Impaired Respiratory Health and Life Course Transitions From Health to Chronic Lung Disease.
Review in Chest, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 26 citations in OpenAlex.
- Genetic Susceptibility to Impaired Lung Function in Underground Coal Miners from Kazakhstan.Genes · 2026Article
- From ideal respiratory health to chronic lung disease: indicators of impaired respiratory health.Expert review of respiratory medicine · 2026Review
- Review
- Global trends and inequalities in environmental risk-attributable chronic obstructive pulmonary disease mortality among adults aged 80+ years, 1990-2021: an analysis of the Global Burden of Disease Study 2021.Journal of thoracic disease · 2026Article
- Progenitor Resilience and the Early Onset of Chronic Lung Diseases: NHLBI workshop report.American journal of respiratory cell and molecular biology · 2026Article
- Wildfire smoke exposure and persistent respiratory symptoms and illness: a retrospective cohort study.Respiratory research · 2026Article
- Prognostic comparison of ablation and laser excision in a population-based cohort of stage III-IV pulmonary malignant tumors.Journal of cardiothoracic surgery · 2026Article
- Respiratory injuries among California career firefighters, 2000-2019.Annals of the American Thoracic Society · 2026Article
- Identifying early-life, environmental, and social stressors as key predictors of U.S. respiratory failure mortality: a machine learning study.Frontiers in public health · 2026Article
- Associations of chronic lung disease, insufficient sleep, and pain with incident frailty in Chinese middle-aged and older adults.Epidemiology and health · 2026Article
- Diminished lung function mediating the associations between blood levels of volatile organic compounds and respiratory morbidity and mortality.Scientific reports · 2025Article
- From Birth to Breathless: The Confluence of Early-Life Tobacco Exposure and Genetics in Idiopathic Pulmonary Fibrosis.Annals of the American Thoracic Society · 2025Article
- Airway Mucus Plugs in Community-Living Adults: A Study Protocol.medRxiv : the preprint server for health sciences · 2024Article
- Proteomic Biomarkers of Quantitative Interstitial Abnormalities in COPDGene and CARDIA Lung Study.American journal of respiratory and critical care medicine · 2024Article
- A Plant-Centered Diet is Inversely Associated With Radiographic Emphysema: Findings from the CARDIA Lung Study.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2024Article
- Centrilobular emphysema and airway dysanapsis: factors associated with low respiratory function in younger smokers.ERJ open research · 2024Article
- Airway Mucus Plugs in Community-Living Adults: A Study Protocol.Journal of clinical & experimental pathology · 2024Article
- Cardiovascular Autonomic Function and Incident Chronic Obstructive Pulmonary Disease Hospitalizations in Atherosclerosis Risk in Communities.Annals of the American Thoracic Society · 2023Article
- Low-Normal FVC Trajectory Starting in Early Adulthood and Risk of Future Interstitial Abnormalities.American journal of respiratory and critical care medicine · 2023Article
- Computed tomography measure of lung injury and future interstitial features: the CARDIA Lung Study.ERJ open research · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Primary prevention and interception of chronic lung disease are essential in the effort to reduce the morbidity and mortality caused by respiratory conditions. In this review, we apply a life course approach that examines exposures across the life span to identify risk factors that are associated with not only chronic lung disease but also an intermediate phenotype between ideal lung health and lung disease, termed "impaired respiratory health." Notably, risk factors such as exposure to tobacco smoke and air pollution, as well as obesity and physical fitness, affect respiratory health across the life course by being associated with both abnormal lung growth and lung function decline. We then discuss the importance of disease interception and identifying those at highest risk of developing chronic lung disease. This work begins with understanding and detecting impaired respiratory health, and we review several promising molecular biomarkers, predictive symptoms, and early imaging findings that may lead to a better understanding of this intermediate phenotype.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.