Evidence map›Paper›PMID 33865432›Full record

ReviewJournal of nanobiotechnology2021

Nanoparticle-mediated synergistic chemoimmunotherapy for tailoring cancer therapy: recent advances and perspectives.

Rafieh Bagherifar, Seyed Hossein Kiaie, Zahra Hatami, Armin Ahmadi, Abdolvahid Sadeghnejad, Behzad Baradaran, Reza Jafari, Yousef Javadzadeh

Open access · goldAbstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 55 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 2 countries.

Rafieh BagherifarStudent Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Seyed Hossein KiaieStudent Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Zahra HatamiDepartment of Immunology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Armin AhmadiDepartment of Chemical & Materials Engineering, The University of Alabama in Huntsville, Huntsville, AL, 35899, USA.
Abdolvahid SadeghnejadCancer Research Center, Semnan University of Medical Sciences, Semnan, Iran.
Behzad BaradaranImmunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Reza JafariSolid Tumor Research Center, Cellular and Molecular Medicine Institute, Urmia University of Medical Sciences, Shafa St, Ershad Blvd., P.O. BoX: 1138, 57147, Urmia, Iran. Jafari.reza@umsu.ac.ir.
Yousef JavadzadehBiotechnology Research Center, and Faculty of Pharmacy, Tabriz University of Medical Science, 5166-15731, Tabriz, Iran. javadzadehy@yahoo.com.
Tabriz University of Medical Sciences · IRKermanshah University of Medical Sciences · IRSemnan University of Medical Sciences · IRTarbiat Modares University · IRUniversity of Alabama in Huntsville · USUniversity of Tabriz · IRUrmia University of Medical Sciences

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nowadays, a potent challenge in cancer treatment is considered the lack of efficacious strategy, which has not been able to significantly reduce mortality. Chemoimmunotherapy (CIT) as a promising approach in both for the first-line and relapsed therapy demonstrated particular benefit from two key gating strategies, including chemotherapy and immunotherapy to cancer therapy; therefore, the discernment of their participation and role of potential synergies in CIT approach is determinant. In this study, in addition to balancing the pros and cons of CIT with the challenges of each of two main strategies, the recent advances in the cancer CIT have been discussed. Additionally, immunotherapeutic strategies and the immunomodulation effect induced by chemotherapy, which boosts CIT have been brought up. Finally, harnessing and development of the nanoparticles, which mediated CIT have expatiated in detail.

Indexed as

Adaptive ImmunityAnimalsAntibodies, MonoclonalCombined Modality TherapyDrug SynergismDrug TherapyHumansImmunotherapyNanoparticlesNeoplasmsAntibodies, MonoclonalChemoimmunotherapyChemotherapyCytokinesImmunotherapyMonoclonal antibodyNanoparticles

Identifiers

PMID33865432
PMCPMC8052859
OpenAlexW3154425738

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.