Evidence map›Paper›PMID 33865379›Full record

ArticleBMC palliative care2021

Palliative care in day-hospital for advanced cancer patients: a study protocol for a multicentre randomized controlled trial.

Laura Marret, Amélie Anota, Lorraine Waechter, Celine Laouisset, Timothee Marchal, Alexis Burnod, Elisabeth Angellier, Oum El Kheir Djoumakh, Clemence Thebaut, Anne Brédart and 3 more

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMC palliative care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04604873 (The Integrated Support and Palliative in Cancer Day-care Hospital for Patients With Advanced Cancers), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04604873 nacompletednot on this map

The Integrated Support and Palliative in Cancer Day-care Hospital for Patients With Advanced Cancers: Impact on Quality of Life, Care Pathways and Support for Caregivers

TypeinterventionalSponsorInstitut CurieRan2020 to 2025Enrolled144ConditionsCancer, AdvancedArmsHospital day care follow-up
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Laura MarretDepartment of Supportive and Palliative Care, Institut Curie, Paris, France. laura.thery@curie.fr.ORCID 0000-0003-2978-6492
Amélie AnotaBiostatistics Unit, DRCI, Centre Léon Bérard, Lyon, France.
Lorraine WaechterDepartment of Supportive and Palliative Care, Hôpital Cochin, Paris, France.
Celine LaouissetDepartment of Supportive and Palliative Care, Institut Curie, Paris, France.
Timothee MarchalDepartment of Supportive and Palliative Care, Institut Curie, Paris, France.
Alexis BurnodDepartment of Supportive and Palliative Care, Institut Curie, Paris, France.
Elisabeth AngellierDepartment of Supportive and Palliative Care, Institut Curie, Saint Cloud, Paris, France.
Oum El Kheir DjoumakhMethodological and Quality of Life Unit in Oncology (INSERM 1098), University Hospital, Besançon, France.
Clemence ThebautUniversité de Limoges, UMR 1094 (NET), Limoges, France.
Anne BrédartDepartment of Psycho-Oncology, Institut Curie, Paris, France.
Sylvie DolbeaultDepartment of Psycho-Oncology, Institut Curie, Paris, France.
Jean-Christophe MinoDepartment of Medical Ethics, Sorbonne University Medical School, Paris, France.
Carole BouleucDepartment of Supportive and Palliative Care, Institut Curie, Paris, France.

Funding

Institut National Du Cancer N°2019-006
6 · The paper itself

Abstract

backgroundTeam-based and timely integrated palliative care is a gold standard of care in oncology, but issues concerning its optimal organization remain. Palliative Care in Day-Hospital (PCDH) could be one of the most efficient service model of palliative care to deliver interdisciplinary and multidimensional care addressing the complex supportive care needs of patients with advanced cancer. We hypothesize that, compared to conventional outpatient palliative care, PCDH allows the clinical benefits of palliative care to be enhanced. METHODS/

designThis study is a multicentre parallel group trial with stratified randomization. Patient management in PCDH will be compared to conventional outpatient palliative care. The inclusion criteria are advanced cancer patients referred to a palliative care team with an estimated life expectancy of more than 2 months and less than 1 year. The primary endpoint is health-related quality of life with deterioration-free survival based on the EORTC QLQ-C30 questionnaire. The secondary objectives are the following: increase in patient satisfaction with care using the EORTC PATSAT-C33 and OUT-PATSAT7 questionnaires, better understanding of the prognosis using the PTPQ questionnaire and advance care planning; decrease in the need for supportive care among relatives using the SCNS-P&C-F questionnaire, and reduction in end-of-life care aggressiveness. Patients will complete one to five questionnaires on a tablet before each monthly visit over 6 months and will be followed for 1 year. A qualitative study will take place, aiming to understand the specificity of palliative care management in PCDH. Cost-effectiveness, cost-utility and, an additional economic evaluation based on capability approach will be conducted from a societal point of view. DISCUSSION: The first strength of this study is that it combines the main relevant outcomes assessing integrated palliative care; patient quality of life and satisfaction; discussion of the prognosis and advance care planning, family well-being and end-of-life care aggressiveness. The second strength of the study is that it is a mixed-method study associating a qualitative analysis of the specificity of PCDH organization, with a medical-economic study to analyse the cost of care.

trial registrationName of the registry: IDRCB 2019-A03116-51 Trial registration number: NCT04604873 Date of registration: October 27, 2020 URL of trial registry record.

Indexed as

NeoplasmsTerminal CareHospitalsHumansMulticenter Studies as TopicPalliative CareQuality of LifeRandomized Controlled Trials as TopicAdvanced cancerEnd-of-life carePalliative careQuality of lifeStudy design

Identifiers

PMID33865379
PMCPMC8053288

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.