Evidence map›Paper›PMID 33865314›Full record

ArticleBMC infectious diseases2021

Comparison of clinical features on admission between coronavirus disease 2019 and influenza a among children: a retrospective study in China.

Feng Liang, Xianfeng Wang, Jianbo Shao, Jun Chen, Lei Liu, Hui Li, Yi Xu, Liya He, Huiying Liang, Kuanrong Li and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Comparison of the Clinical and Laboratory Features of COVID and Influenza in Children.Mediterranean journal of hematology and infectious diseases · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Feng Liang *Clinical Data Center, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, 510623, Guangdong, China.
Xianfeng Wang *Department of Pediatric, The Third People's Hospital of Shenzhen, Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen, Guangdong, China.
Jianbo Shao *Department of Pediatric, Wuhan Children's Hospital, Wuhan, 430000, Hubei, China.
Jun ChenDepartment of Pediatric, The Third People's Hospital of Shenzhen, Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen, Guangdong, China.
Lei LiuDepartment of Infectious Disease, The Third People's Hospital of Shenzhen, Shenzhen, 518112, Guangdong, China. liulei3322@aliyun.com.
Hui LiDepartment of Pediatric, Wuhan Children's Hospital, Wuhan, 430000, Hubei, China. tianyirabbit@163.com.
Yi XuDepartment of Pediatric, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Liya HeDepartment of Pediatric, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Huiying LiangClinical Data Center, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, 510623, Guangdong, China.
Kuanrong LiClinical Data Center, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, 510623, Guangdong, China. lik@gwcmc.org.
Sitang GongDepartment of Pediatric, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Huimin XiaClinical Data Center, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, 510623, Guangdong, China.
Guangzhou Medical University · CNSouthern University of Science and Technology · CNWuhan Children's Hospital · CNShenzhen Third People’s Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronavirus disease 2019 (COVID-19) share similar symptoms with influenza A (IA), but it is more worthwhile to understand the disparities of the two infections regarding their clinical characteristics on admission.

methodsA total of 71 age-matched pediatric IA and COVID-19 patient pairs were formed and their clinical data on admission were compared.

resultsFever, cough, nasal congestion and nausea/vomiting were the most common symptoms on admission for both infections but occurred less often in COVID-19. The IA patients were more likely to have lower-than-normal levels of lymphocyte count and percentage and to have higher-than-normal levels of activated partial thromboplastin time, prothrombin time, serum C-reactive protein, and serum procalcitonin, while the COVID-19 patients had higher odds of having lower-than-normal levels of neutrophil count and percentage.

conclusionsThis study suggests that influenza A is more symptomatic than COVID-19 for children and might be an overall more severe infection at the time of admission.

Indexed as

Diagnosis, DifferentialSymptom AssessmentAdolescentChildChild, PreschoolChinaCoughCOVID-19C-Reactive ProteinFemaleFeverHospitalizationHumansInfantInfant, NewbornInfluenza, HumanC-Reactive ProteinProcalcitoninCoronavirus disease 2019Influenza aPediatricsRetrospective study

Identifiers

PMID33865314
PMCPMC8052833
OpenAlexW3152766940

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.