Evidence map›Paper›PMID 33864824›Full record

ReviewInternational journal of radiation oncology, biology, physics2021

Modeling of Tumor Control Probability in Stereotactic Body Radiation Therapy for Adrenal Tumors.

Priscilla K Stumpf, Ellen D Yorke, Issam El Naqa, Kyle C Cuneo, Jimm Grimm, Karyn A Goodman

Open access · greenAbstract readReview
In one paragraph

Review in International journal of radiation oncology, biology, physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Priscilla K StumpfDepartment of Radiation Oncology, University of Colorado Cancer Center, Aurora, Colorado. Electronic address: priscilla.stumpf@cuanschutz.edu.
Ellen D YorkeDepartment of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York.
Issam El NaqaDepartment of Radiation Oncology, University of Michigan, Ann Arbor, Michigan; Department of Radiation Oncology, Moffitt Cancer Center, Tampa, Florida.
Kyle C CuneoDepartment of Radiation Oncology, University of Michigan, Ann Arbor, Michigan.
Jimm GrimmDepartment of Radiation Oncology, Geisinger Health System, Danville, Pennsylvania; Department of Medical Imaging and Radiation Sciences, Thomas Jefferson University, Philadelphia, Pennsylvania.
Karyn A GoodmanDepartment of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, New York.
University of Michigan–Ann Arbor · USIcahn School of Medicine at Mount Sinai · USMemorial Sloan Kettering Cancer Center · USThomas Jefferson University · USUniversity of Colorado Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

purposeStereotactic body radiation therapy (SBRT) in the management of adrenal metastases is emerging as a well-tolerated, effective method of treatment for patients with limited metastatic disease. SBRT planning and treatment utilization are widely variable, and publications report heterogeneous radiation dose fractionation schemes and treatment outcomes. The objective of this analysis was to review the current literature on SBRT for adrenal metastases and to develop treatment guidelines and a model for tumor control probability of SBRT for adrenal metastases based on these publications. METHODS AND MATERIALS: A literature search of all studies on SBRT for adrenal metastases published from 2008 to 2017 was performed, and outcomes in these studies were reviewed. Local control (LC) rates were fit to a statistically significant Poisson model using maximum likelihood estimation techniques.

resultsOne-year LC greater than 95% was achieved at an approximated biological equivalent dose with α/β = 10 Gy of 116.4 Gy.

conclusionsWhile respecting normal tissue tolerances, tumor doses greater than or equal to a biological equivalent dose with α/β = 10 Gy of 116.4 Gy are recommended to achieve high LC. Further studies following unified reporting standards are needed for more robust prediction.

Indexed as

Adrenal Gland NeoplasmsHumansLikelihood FunctionsModels, BiologicalModels, TheoreticalOrgans at RiskPoisson DistributionProbabilityRadiation Dose HypofractionationRadiation ToleranceRadiosurgeryRelative Biological EffectivenessTreatment Outcome

Identifiers

PMID33864824
PMCPMC9446062
OpenAlexW3155745616

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.