Evidence map›Paper›PMID 33864577›Full record

ArticleInternational ophthalmology2021

The effect of COVID-19 pandemic restrictions on neovascular AMD patients treated with treat-and-extend protocol.

Mehmet Orkun Sevik, Aslan Aykut, Gamze Özkan, Volkan Dericioğlu, Özlem Şahin

Abstract read
In one paragraph

Article in International ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mehmet Orkun SevikDepartment of Ophthalmology, Marmara University School of Medicine, Fevzi Çakmak Mah, Muhsin Yazıcıoğlu Cd, No: 10, Marmara Üniversitesi Pendik Eğitim ve Araştırma Hastanesi, Kat: 3, Oftalmoloji Servisi, Pendik, 34899, Istanbul, Turkey. m.orkunsevik@gmail.com.ORCID http://orcid.org/0000-0001-7130-4798
Aslan AykutDepartment of Ophthalmology, Marmara University School of Medicine, Fevzi Çakmak Mah, Muhsin Yazıcıoğlu Cd, No: 10, Marmara Üniversitesi Pendik Eğitim ve Araştırma Hastanesi, Kat: 3, Oftalmoloji Servisi, Pendik, 34899, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-5426-1992
Gamze ÖzkanDepartment of Ophthalmology, Marmara University School of Medicine, Fevzi Çakmak Mah, Muhsin Yazıcıoğlu Cd, No: 10, Marmara Üniversitesi Pendik Eğitim ve Araştırma Hastanesi, Kat: 3, Oftalmoloji Servisi, Pendik, 34899, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-5526-691X
Volkan DericioğluDepartment of Ophthalmology, Marmara University School of Medicine, Fevzi Çakmak Mah, Muhsin Yazıcıoğlu Cd, No: 10, Marmara Üniversitesi Pendik Eğitim ve Araştırma Hastanesi, Kat: 3, Oftalmoloji Servisi, Pendik, 34899, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-6264-5304
Özlem ŞahinDepartment of Ophthalmology, Marmara University School of Medicine, Fevzi Çakmak Mah, Muhsin Yazıcıoğlu Cd, No: 10, Marmara Üniversitesi Pendik Eğitim ve Araştırma Hastanesi, Kat: 3, Oftalmoloji Servisi, Pendik, 34899, Istanbul, Turkey.ORCID http://orcid.org/0000-0003-2907-2852

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the adherence rate of neovascular age-related macular degeneration (nAMD) patients in treat-and-extend (TAE) protocol to their anti-vascular endothelial growth factor (anti-VEGF) intravitreal injection (IVI) appointments and to evaluate the functional and anatomical outcomes of the patients who attended and did not attend their IVI appointments during the coronavirus disease 2019 (COVID-19) restriction period (RP).

methodsThe patients with nAMD having IVI appointments between March 16 and June 1, 2020 (RP in Turkey) were included in this retrospective study. For adherence analysis, the patients who attended (Group 1, n = 44) and who did not attend (Group 2, n = 60) their IVI appointment visits during the RP (V

resultsThe adherence rate of the patients to V

conclusionsMore than half of the scheduled nAMD patients in TAE protocol missed their IVI visits during the RP, which resulted in a delay of their treatments. The delay of IVI treatment in those patients resulted in an increase in OCT disease activity and a decrease in BCVA.

Indexed as

COVID-19Wet Macular DegenerationAngiogenesis InhibitorsHumansIntravitreal InjectionsPandemicsReceptors, Vascular Endothelial Growth FactorRecombinant Fusion ProteinsRetrospective StudiesSARS-CoV-2Tomography, Optical CoherenceTreatment OutcomeVascular Endothelial Growth Factor AVisual AcuityAngiogenesis InhibitorsReceptors, Vascular Endothelial Growth FactorRecombinant Fusion ProteinsVascular Endothelial Growth Factor ACoronavirus disease-2019COVID-19nAMDNeovascular age-related macular degenerationTreat-and-extend protocol

Identifiers

PMID33864577
PMCPMC8052549

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.