Evidence map›Paper›PMID 33864558›Full record

ArticleJournal of autism and developmental disorders2022

Autism Spectrum Disorder and Mental Health Problems: Patterns of Difficulties and Longitudinal Trajectories in a Population-Based Twin Sample.

Emma Colvert, Emily Simonoff, Simone J Capp, Angelica Ronald, Patrick Bolton, Francesca Happé

Open access · hybridAbstract readTwin Study
In one paragraph

Article in Journal of autism and developmental disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Assessing Psychiatric Symptoms in Autistic Youth Using the K-CATJournal of autism and developmental disorders · 2026
    Article
  4. Article
  5. Review
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  7. Article
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  16. Mental health and social difficulties of late-diagnosed autistic children, across childhood and adolescence.Journal of child psychology and psychiatry, and allied disciplines · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Emma ColvertSocial, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, PO80, Denmark Hill, London, SE5 8AF, UK. emma.colvert@kcl.ac.uk.ORCID http://orcid.org/0000-0002-7513-5570
Emily SimonoffDepartment of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, Denmark Hill, London, SE5 8AF, UK.
Simone J CappSocial, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, PO80, Denmark Hill, London, SE5 8AF, UK.
Angelica RonaldDepartment of Psychological Sciences, Birkbeck, University of London, Malet Street, London, WC1E 7HX, UK.
Patrick BoltonDepartment of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, Denmark Hill, London, SE5 8AF, UK.
Francesca HappéSocial, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, PO80, Denmark Hill, London, SE5 8AF, UK.
King's College London · GBBirkbeck, University of London · GB

Funding

Medical Research Council G0500870
6 · The paper itself

Abstract

There is increasing concern regarding additional psychiatric problems that co-occur with Autism Spectrum Disorder (ASD), as reflected in recent changes to diagnostic schemes. However, there remains little research with population-based samples across childhood. We report on additional problems, as measured by the Strengths and Difficulties Questionnaire, in a population-based sample of 135 twins with ASD, 55 non-ASD co-twins, and 144 comparison twins low in ASD traits. Frequencies, associated demographic factors, and changes in mental health difficulties from age 4 to 13 years are presented. Our data confirm the high rates of additional difficulties reported in previous studies, and suggest that the profile, associated risk factors and longitudinal course of additional difficulties in ASD may differ from those in typically-developing populations.

Indexed as

Autism Spectrum DisorderAdolescentChildChild, PreschoolDiseases in TwinsHumansMental HealthPhenotypeTwinsAdolescentsAutism spectrum disordersLongitudinal researchMental health

Identifiers

PMID33864558
PMCPMC8854265
OpenAlexW3156788527

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.