Evidence map›Paper›PMID 33864418›Full record

ArticleMicrocirculation (New York, N.Y. : 1994)2021

Skin microvascular function and renal hemodynamics in overweight patients with type 2 diabetes: A cross-sectional study.

Emma J Bouman, Mark M Smits, Erik J van Bommel, Marcel H A Muskiet, Anne C Hesp, Erik H Serné, Jaap A Joles, Daniël H van Raalte

Open access · hybridAbstract read
In one paragraph

Article in Microcirculation (New York, N.Y. : 1994), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Emma J BoumanDiabetes Center, Department of Internal Medicine, Amsterdam University Medical Center, Location VUMC, Amsterdam, The Netherlands.ORCID 0000-0001-6559-8961
Mark M SmitsDiabetes Center, Department of Internal Medicine, Amsterdam University Medical Center, Location VUMC, Amsterdam, The Netherlands.
Erik J van BommelDiabetes Center, Department of Internal Medicine, Amsterdam University Medical Center, Location VUMC, Amsterdam, The Netherlands.
Marcel H A MuskietDiabetes Center, Department of Internal Medicine, Amsterdam University Medical Center, Location VUMC, Amsterdam, The Netherlands.
Anne C HespDiabetes Center, Department of Internal Medicine, Amsterdam University Medical Center, Location VUMC, Amsterdam, The Netherlands.
Erik H SernéDiabetes Center, Department of Internal Medicine, Amsterdam University Medical Center, Location VUMC, Amsterdam, The Netherlands.
Jaap A JolesDepartment of Nephrology and Hypertension, Utrecht University Medical Center, Utrecht, The Netherlands.
Daniël H van RaalteDiabetes Center, Department of Internal Medicine, Amsterdam University Medical Center, Location VUMC, Amsterdam, The Netherlands.
Amsterdam University Medical Centers · NLUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDiabetic kidney disease is a microvascular complication of diabetes. Here, we assessed the association between skin microvascular function and renal hemodynamic function in a cohort of well-phenotyped adults with type 2 diabetes (T2D).

methodsWe included 81 overweight/obese adults (age: 62 ± 8 years; BMI: 32 ± 4 kg/m

resultsSkin capillary density was 45 ± 10 capillaries/mm

conclusionThese findings indicate that microvascular dysfunction in overweight adults with T2D is associated with lower mGFR and ERPF and higher ERVR. We hypothesize that increased renal vascular resistance may contribute to glomerular dysfunction due to impaired renal perfusion.

Indexed as

Diabetes Mellitus, Type 2AgedCross-Sectional StudiesGlomerular Filtration RateHemodynamicsHumansKidneyMiddle AgedOverweightcapillary recruitmentdiabetic kidney diseasemeasured GFRmicrovascular dysfunctionrenal hemodynamicstype 2 diabetes

Identifiers

PMID33864418
PMCPMC8459253
OpenAlexW3155554819

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.