ReviewJournal of endocrinological investigation2021
Evaluation of thyroid nodules by shear wave elastography: a review of current knowledge.
Review in Journal of endocrinological investigation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- 2023 European Thyroid Association Clinical Practice Guidelines for thyroid nodule management.European thyroid journal · 2023Guideline
- Serum microRNAs as biomarkers for the diagnosis of papillary thyroid carcinoma: a meta-analysis.Bosnian journal of basic medical sciences · 2022Pooled it
- SuperSonic shear imaging for the differentiation between benign and malignant thyroid nodules: a meta-analysis.Journal of endocrinological investigation · 2022Pooled it
- Article
- Force-controlled robotic ultrasound elastography enhances diagnostic consistency for thyroid nodules.Insights into imaging · 2026Article
- Predictive value of real-time shear wave elastography combined with serum thyroglobulin in thyroid cancer.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026Article
- The diagnostic value of two-dimensional shear-wave elastography in identifying malignant lesions in lymph nodes: a prospective study.Scientific reports · 2025Article
- Contrast-enhanced ultrasound combined with shear wave elastography in the diagnosis of C-TIRADS category 4 thyroid nodules.Quantitative imaging in medicine and surgery · 2025Article
- Role of Ultrasound Elastography and Contrast-Enhanced Ultrasound (CEUS) in Diagnosis and Management of Malignant Thyroid Nodules-An Update.Diagnostics (Basel, Switzerland) · 2025Review
- Integrating shear wave elastography into clinical prediction of Graves' disease recurrence: a novel risk scoring system.Frontiers in endocrinology · 2025Article
- Multimodal ultrasound features for distinguishing classic and aggressive subtypes of papillary thyroid carcinoma.Frontiers in endocrinology · 2025Article
- Thyroid Nodule Characterization: Overview and State of the Art of Diagnosis with Recent Developments, from Imaging to Molecular Diagnosis and Artificial Intelligence.Biomedicines · 2024Review
- Application of shear wave elastography in the management of thyroid nodules in children and adolescents: our experience and a review of the literature.Frontiers in endocrinology · 2024Review
- A new LNC89/LNC60-Col11a2 axis revealed by whole-transcriptome analysis may be associated with goiters related to excess iodine nutrition.Frontiers in endocrinology · 2024Article
- Diagnostic efficacy of data mining method based on multimodal ultrasound for papillary thyroid carcinoma.Frontiers in oncology · 2024Article
- Research progress in pelvic floor ultrasound for assessing the morphology and function of levator ani muscle in women.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023Article
- A Comparative Analysis of Strain and 2D Shear Wave Elastography in the Diagnosis of Autoimmune Thyroiditis in Pediatric Patients.Biomedicines · 2023Article
- Diagnostic value of endobronchial ultrasound elastography in differentiating between benign and malignant hilar and mediastinal lymph nodes: a retrospective study.Quantitative imaging in medicine and surgery · 2023Article
- Application of decision tree algorithms to predict central lymph node metastasis in well-differentiated papillary thyroid carcinoma based on multimodal ultrasound parameters: a retrospective study.Quantitative imaging in medicine and surgery · 2023Article
- Assessment of Thyroid Stiffness and Viscosity in Autoimmune Thyroiditis Using Novel Ultrasound-Based Techniques.Biomedicines · 2023Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeShear wave elastography (SWE), as a tool for diagnosing thyroid malignancy, has gathered considerable attention during the past decade. Diverging results exist regarding the diagnostic performance of thyroid SWE.
methodsA comprehensive literature review of thyroid SWE was conducted using the terms "Thyroid" and "shear wave elastography" in PubMed.
resultsThe majority of studies found SWE promising for differentiating malignant and benign thyroid nodules on a group level, whereas results are less convincing on the individual level due to huge overlap in elasticity indices. Further, there is lack of consensus on the optimum outcome reflecting nodule elasticity and the cut-off point predicting thyroid malignancy. While heterogeneity between studies hinders a clinically meaningful meta-analysis, the results are discussed in a clinical perspective with regard to applicability in clinical practice as well as methodological advantages and pitfalls of this technology.
conclusionTechnological as well as biological hindrances seem to exist for SWE to be clinically reliable in assessing benign and malignant thyroid nodules. Structural heterogeneity of thyroid nodules in combination with operator-dependent factors such as pre-compression and selection of scanning plane are likely explanations for these findings. Standardization and consensus on the SWE acquisition process applied in future studies are needed for SWE to be considered a clinically reliable diagnostic tool for detection of thyroid cancer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.