SynthesisLangenbeck's archives of surgery2021
Relationship between diversional stoma and mortality rate in Fournier's gangrene: a systematic review and meta-analysis.
Synthesis in Langenbeck's archives of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Şimşek Index (Kocaeli Fournier’s Gangrene Severity Index, KFGSI): Development and Prognostic Performance of an Admission-Based Mortality Prediction Model for Fournier’s GangreneUlusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026Article
- Surgical fecal diversionWorld journal of critical care medicine · 2026Article
- Defining the Standard of Care in Fournier's Gangrene-An Umbrella Review.European urology open science · 2026Review
- Fournier's gangrene due to rectal cancer: A case report.Molecular and clinical oncology · 2024Article
- Impact of fecal diversion in Perineal Necrotizing Soft Tissue Infection on disease survival: A large retrospective study.Surgery in practice and science · 2024Article
- Fournier's gangrene and fecal diversion. When, in which patients, and what type should I perform?Langenbeck's archives of surgery · 2023Article
- The role of C-reactive protein albumin ratio for predicting mortality in patients with Fournier's gangrene.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2023Article
- Global outcomes and lessons learned in the management of Fournier's gangrene from high-volume centres: findings from a literature review over the last two decades.World journal of urology · 2022Review
- Risk factors for mortality in Fournier's gangrene of anorectal origin.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
- Progress in Multidisciplinary Treatment of Fournier's Gangrene.Infection and drug resistance · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeFournier's gangrene (FG) is a rare potentially lethal necrotising infection of the perineum. While the gold standard management is early and aggressive surgical debridement, the evidence in the literature is unclear as to the role and outcomes of diversional stoma.
methodsA systematic review was conducted to identify studies investigating the relationship between stoma formation and FG. Meta-analyses were performed using a random-effects model.
resultsTwenty-seven studies (n=1482) were included. There was no significant difference in disease severity scores between the stoma and no stoma groups. Mortality rate was significantly higher in patients who required diversional stoma (OR 1.71, 95% CI 1.13-2.59, p=0.01). Significantly more surgical procedures were performed on patients who underwent stoma formation, and the total hospital cost was also higher in this group. This study may have been limited by bias in patients with more fulminant course or sphincter damage requiring stoma as a medical necessity.
conclusionThese findings suggest that the use of diversional stoma in FG is a predictor of poor outcomes. This study demonstrated that mortality rate remained high and a diversional stoma did not reduce risk of mortality as suggested by smaller case series. Its use should therefore be individualised based on disease severity and sphincter damage.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.