Evidence map›Paper›PMID 33863969›Full record

ArticleScientific reports2021

Effectiveness of antimicrobial prophylaxis at 30 versus 60 min before cesarean delivery.

Hadas Rubin, Eyal Rom, Malak Wattad, Khadeje Seh, Natanel Levy, Ayellet Jehassi, Shabtai Romano, Raed Salim

Abstract readComparative Study
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hadas RubinDepartment of Obstetrics and Gynecology, Emek Medical Center, 18101, Afula, Israel.
Eyal RomDepartment of Obstetrics and Gynecology, Emek Medical Center, 18101, Afula, Israel.
Malak WattadDepartment of Obstetrics and Gynecology, Emek Medical Center, 18101, Afula, Israel.
Khadeje SehDepartment of Obstetrics and Gynecology, Emek Medical Center, 18101, Afula, Israel.
Natanel LevyDepartment of Anesthesiology, Emek Medical Center, Afula, Israel.
Ayellet JehassiBiostatistics Unit, Emek Medical Center, Afula, Israel.
Shabtai RomanoDepartment of Obstetrics and Gynecology, Emek Medical Center, 18101, Afula, Israel.
Raed SalimDepartment of Obstetrics and Gynecology, Emek Medical Center, 18101, Afula, Israel. salim_ra@clalit.org.il.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to examine the effect of antibiotic prophylaxis (AP) given within 30 compared to 30-60 min before skin incision on the incidence of infectious morbidity after cesarean delivery (CD). A retrospective cohort study was conducted at a single institution on data between 2014 and 2018. Women who delivered by CD were divided into two groups according to AP timing before skin incision: group 1 within 30 min, and group 2 from 30 to 60 min. The primary outcome was the incidence of any infectious morbidity. Overall, 2989 women were eligible: 2791 in group 1 and 198 in group 2. The primary composite outcome occurred in 125 women (4.48%) in group 1 and 8 women (4.04%) in group 2 (OR, 1.11; 95% CI 0.54-2.31; P = 0.77). The rate of surgical site infection only, was 1.08% in group 1 and 0.51% in group 2 (OR, 2.13; 95% CI 0.29-15.70; P = 0.72). The incidence was comparable between the groups in a separate sub-analysis restricted to laboring CDs and obese women. The rate of infectious morbidity was similar among women who received AP within 30 min and from 30 to 60 min before skin incision.

Indexed as

Antibiotic ProphylaxisAdultAnti-Bacterial AgentsCesarean SectionFemaleHumansIncidenceIsraelPregnancyRetrospective StudiesSurgical Wound InfectionTime FactorsAnti-Bacterial Agents

Identifiers

PMID33863969
PMCPMC8052330

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.