Evidence map›Paper›PMID 33863938›Full record

ArticleScientific reports2021

Structural equation modeling to shed light on the controversial role of climate on the spread of SARS-CoV-2.

Alessia Spada, Francesco Antonio Tucci, Aldo Ummarino, Paolo Pio Ciavarella, Nicholas Calà, Vincenzo Troiano, Michele Caputo, Raffaele Ianzano, Silvia Corbo, Marco de Biase and 7 more

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Alessia Spada *Statistics and Mathematics Area, Department of Economics, University of Foggia, Foggia, Italy.ORCID 0000-0001-8241-6023
Francesco Antonio Tucci *Agorà Biomedical Sciences, Etromapmax Pole, Lesina (FG), Italy.ORCID 0000-0001-6247-5392
Aldo UmmarinoAgorà Biomedical Sciences, Etromapmax Pole, Lesina (FG), Italy. aldo.ummarino@hunimed.eu.ORCID 0000-0002-8623-0338
Paolo Pio CiavarellaAgorà Biomedical Sciences, Etromapmax Pole, Lesina (FG), Italy.
Nicholas CalàAgorà Biomedical Sciences, Etromapmax Pole, Lesina (FG), Italy.
Vincenzo TroianoAgorà Biomedical Sciences, Etromapmax Pole, Lesina (FG), Italy.
Michele CaputoAgorà Biomedical Sciences, Etromapmax Pole, Lesina (FG), Italy.
Raffaele IanzanoAgorà Biomedical Sciences, Etromapmax Pole, Lesina (FG), Italy.
Silvia CorboAgorà Biomedical Sciences, Etromapmax Pole, Lesina (FG), Italy.
Marco de BiaseAgorà Biomedical Sciences, Etromapmax Pole, Lesina (FG), Italy.
Nicola FasciaAgorà Biomedical Sciences, Etromapmax Pole, Lesina (FG), Italy.
Chiara ForteAgorà Biomedical Sciences, Etromapmax Pole, Lesina (FG), Italy.
Giorgio GambacortaAgorà Biomedical Sciences, Etromapmax Pole, Lesina (FG), Italy.
Gabriele MaccioneAgorà Biomedical Sciences, Etromapmax Pole, Lesina (FG), Italy.
Giuseppina PrencipeAgorà Biomedical Sciences, Etromapmax Pole, Lesina (FG), Italy.
Michele TomaiuoloAgorà Biomedical Sciences, Etromapmax Pole, Lesina (FG), Italy.
Antonio TucciAgorà Biomedical Sciences, Etromapmax Pole, Lesina (FG), Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Climate seems to influence the spread of SARS-CoV-2, but the findings of the studies performed so far are conflicting. To overcome these issues, we performed a global scale study considering 134,871 virologic-climatic-demographic data (209 countries, first 16 weeks of the pandemic). To analyze the relation among COVID-19, population density, and climate, a theoretical path diagram was hypothesized and tested using structural equation modeling (SEM), a powerful statistical technique for the evaluation of causal assumptions. The results of the analysis showed that both climate and population density significantly influence the spread of COVID-19 (p < 0.001 and p < 0.01, respectively). Overall, climate outweighs population density (path coefficients: climate vs. incidence = 0.18, climate vs. prevalence = 0.11, population density vs. incidence = 0.04, population density vs. prevalence = 0.05). Among the climatic factors, irradiation plays the most relevant role, with a factor-loading of - 0.77, followed by temperature (- 0.56), humidity (0.52), precipitation (0.44), and pressure (0.073); for all p < 0.001. In conclusion, this study demonstrates that climatic factors significantly influence the spread of SARS-CoV-2. However, demographic factors, together with other determinants, can affect the transmission, and their influence may overcome the protective effect of climate, where favourable.

Indexed as

ClimateModels, TheoreticalAtmospheric PressureCOVID-19HumansHumidityPopulation DensityPrevalenceRainSARS-CoV-2Temperature

Identifiers

PMID33863938
PMCPMC8052355

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.