ArticleNPJ breast cancer2021
Dynamic contrast-enhanced breast MRI features correlate with invasive breast cancer angiogenesis.
Article in NPJ breast cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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Who cites it
51 citing papers in PubMed.
- Low-dose acetylsalicylic acid reduces local inflammation and tissue perfusion in dense breast tissue in postmenopausal women.Breast cancer research : BCR · 2024Trial
- Contrast-enhanced CT radiomics for prediction of recurrence-free survival in gallbladder carcinoma after surgical resection.European radiology · 2022Trial
- DCE-MRI kinetic heterogeneity facilitates the discrimination of benignity and malignancy of breast in combination with the DWI and morphological features.European journal of radiology open · 2026Article
- Influence of virtual dynamic contrast enhanced breast MRI on lesion size, BI-RADS scores and reader confidence.European radiology · 2026Article
- Lightweight Transformer-based knowledge distillation framework for high-dimensional spatiotemporal radiomics in breast cancer risk prediction.Visual computing for industry, biomedicine, and art · 2026Article
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- AI-Driven Breast Cancer Diagnosis: A Systematic Review of Imaging Modalities, Deep Learning, and Explainability.Cancers · 2026Review
- Automated calculation of background parenchymal enhancement as a biomarker of treatment responses and recurrence-free survival in breast cancer.Breast cancer research and treatment · 2026Article
- Tumor heterogeneity index from DCE-MRI for AKT-inhibition responder identification and reveals hot immune microenvironment for patients with breast cancer: a multi-omics analysis of I-SPY2 trial.Breast cancer research : BCR · 2026Article
- Advanced diffusion-weighted imaging of invasive tumor front for identification of macrotrabecular-massive hepatocellular carcinoma: a proof-of-concept study.La Radiologia medica · 2026Article
- MRI-Based Radiomics Model for Classifying Axillary Lymph Node Burden and Disease-Free Survival in Patients With Early-Stage Breast Cancer.Journal of magnetic resonance imaging : JMRI · 2026Article
- Article
- Ground-Glass Enhancement on Contrast-Enhanced Mammography: A CT-Inspired Qualitative Descriptor for Breast Lesion Characterization.Journal of clinical medicine · 2026Article
- BreastDCEDL: A standardized deep learning-ready breast DCE-MRI dataset of 2,070 patients.Scientific data · 2026Article
- A deep learning model based on multiphase DCE-MRI for preoperative prediction of Ki-67 expression in breast cancer.Frontiers in oncology · 2026Article
- Hemodynamic Inflow-Outflow Profiling as an Integrated DCE-MRI Biomarker for Diagnosis and Risk Stratification in Breast Cancer: A Multicenter Retrospective Study.Breast cancer (Dove Medical Press) · 2026Article
- Skeletal muscle dysfunction induced by cancer immunotherapy: mechanistics insights and surgical implications.Frontiers in immunology · 2026Review
- The role of magnetic resonance imaging (MRI) in breast cancer molecular subtypes.Polish journal of radiology · 2026Review
- Early identification of neoadjuvant therapy non-response via multimodal immune-imaging biomarkers in breast cancer.Frontiers in immunology · 2026Article
- Ultrasound-guided diffuse optical tomography: an adjunct to ultrasound that can reduce unnecessary breast biopsies.Breast cancer research : BCR · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Angiogenesis is a critical component of breast cancer development, and identification of imaging-based angiogenesis assays has prognostic and treatment implications. We evaluated the association of semi-quantitative kinetic and radiomic breast cancer features on dynamic contrast-enhanced (DCE)-MRI with microvessel density (MVD), a marker for angiogenesis. Invasive breast cancer kinetic features (initial peak percent enhancement [PE], signal enhancement ratio [SER], functional tumor volume [FTV], and washout fraction [WF]), radiomics features (108 total features reflecting tumor morphology, signal intensity, and texture), and MVD (by histologic CD31 immunostaining) were measured in 27 patients (1/2016-7/2017). Lesions with high MVD levels demonstrated higher peak SER than lesions with low MVD (mean: 1.94 vs. 1.61, area under the receiver operating characteristic curve [AUC] = 0.79, p = 0.009) and higher WF (mean: 50.6% vs. 22.5%, AUC = 0.87, p = 0.001). Several radiomics texture features were also promising for predicting increased MVD (maximum AUC = 0.84, p = 0.002). Our study suggests DCE-MRI can non-invasively assess breast cancer angiogenesis, which could stratify biology and optimize treatments.
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Registered trials
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