Evidence map›Paper›PMID 33863871›Full record

ArticleSignal transduction and targeted therapy2021

CRISPR base editor treats premature-aging syndrome.

Ping Lin, Jianxin Jiang, Min Wu

Abstract readComment
In one paragraph

Article in Signal transduction and targeted therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Germline stem cells in human.Signal transduction and targeted therapy · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Ping LinWound Trauma Medical Center, State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, Army Medical University, Chongqing, China. bio_lp@126.com.ORCID 0000-0002-4281-2440
Jianxin JiangWound Trauma Medical Center, State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, Army Medical University, Chongqing, China. hellojjx@126.com.
Min WuDepartment of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND, USA. min.wu@und.edu.ORCID 0000-0003-1205-982X

Funding

Lung innate immunity against bacterial infectionR01AI109317 · NIAID · UNIVERSITY OF NORTH DAKOTA · PI WU, MIN · 2014 to 2018
$1.7M
Long noncoding RNAs interact with miRNAs to regulate inflammatory responseR01AI138203 · NIAID · UNIVERSITY OF NORTH DAKOTA · PI COMBS, COLIN K · 2018 to 2021
$1.4M
NIAID NIH HHS R01 AI109317NIAID NIH HHS R01 AI138203
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Aging, PrematureClustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsGene EditingHumans

Identifiers

PMID33863871
PMCPMC8050807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.