Evidence map›Paper›PMID 33863744›Full record

ArticleThe European respiratory journal2021

The coexistence of asthma and COPD: risk factors, clinical history and lung function trajectories.

Alessandro Marcon, Francesca Locatelli, Shyamali C Dharmage, Cecilie Svanes, Joachim Heinrich, Bénédicte Leynaert, Peter Burney, Angelo Corsico, Gulser Caliskan, Lucia Calciano and 13 more

Open access · hybridAbstract read
In one paragraph

Article in The European respiratory journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Identifying risk factors for COPD and adult-onset asthma: an umbrella review.European respiratory review : an official journal of the European Respiratory Society · 2023
    Pooled it
  2. Review
  3. Article
  4. Article
  5. International journal of chronic obstructive pulmonary disease · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Plasma Levels of CXCL9 and MCP-3 are Increased in Asthma-COPD Overlap (ACO) Patients.International journal of chronic obstructive pulmonary disease · 2025
    Article
  11. Plasma Levels of CXCL9 and MCP-3 are Increased in Asthma-COPD Overlap (ACO) Patients.International journal of chronic obstructive pulmonary disease · 2025
    Article
  12. Contributions of Medical Greenhouse Gases to Climate Change and Their Possible Alternatives.International journal of environmental research and public health · 2024
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Asthma and Tobacco Smoking.Journal of personalized medicine · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors at 15 institutions in 13 countries.

Alessandro MarconUnit of Epidemiology and Medical Statistics, Dept of Diagnostics and Public Health, University of Verona, Verona, Italy alessandro.marcon@univr.it.ORCID 0000-0002-2778-658X
Francesca LocatelliUnit of Epidemiology and Medical Statistics, Dept of Diagnostics and Public Health, University of Verona, Verona, Italy.
Shyamali C DharmageAllergy and Lung Health Unit, School of Population and Global Health, The University of Melbourne, Melbourne, Australia.ORCID 0000-0002-4388-784X
Cecilie SvanesCentre for International Health, Dept of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
Joachim HeinrichInstitute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital of Ludwig Maximilians University, Comprehensive Pneumology Centre Munich, German Centre for Lung Research, Munich, Germany.
Bénédicte LeynaertUniversité Paris-Saclay, UVSQ, Université Paris-Sud, Inserm, Équipe d'Épidémiologie Respiratoire Intégrative, CESP, Villejuif, France.ORCID 0000-0001-5045-2492
Peter BurneyNational Heart and Lung Institute, Imperial College London, London, UK.
Angelo CorsicoDivision of Respiratory Diseases, IRCCS Policlinico San Matteo Foundation - Dept of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy.
Gulser CaliskanUnit of Epidemiology and Medical Statistics, Dept of Diagnostics and Public Health, University of Verona, Verona, Italy.ORCID 0000-0003-2370-349X
Lucia CalcianoUnit of Epidemiology and Medical Statistics, Dept of Diagnostics and Public Health, University of Verona, Verona, Italy.
Thorarinn GislasonDept of Sleep, Landspitali University Hospital, Reykjavik, Iceland.
Christer JansonDept of Medical Sciences: Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden.ORCID 0000-0001-5093-6980
Deborah JarvisNational Heart and Lung Institute, Imperial College London, London, UK.ORCID 0000-0002-1753-3896
Rain JõgiLung Clinic, Tartu University Hospital, Tartu, Estonia.ORCID 0000-0003-0869-6914
Theodore LytrasInstitute for Global Health (ISGlobal), Barcelona, Spain.ORCID 0000-0002-4146-4122
Andrei MalinovschiDept of Medical Sciences: Clinical Physiology, Uppsala University, Uppsala, Sweden.ORCID 0000-0002-4098-7765
Nicole Probst-HenschDept of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland.
Kjell TorenOccupational and Environmental Medicine, School of Public Health, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Lidia CasasEpidemiology and Social Medicine, University of Antwerp, Antwerp, Belgium.
Giuseppe VerlatoUnit of Epidemiology and Medical Statistics, Dept of Diagnostics and Public Health, University of Verona, Verona, Italy.
Judith Garcia-AymerichInstitute for Global Health (ISGlobal), Barcelona, Spain.ORCID 0000-0002-7097-4586
Simone AccordiniUnit of Epidemiology and Medical Statistics, Dept of Diagnostics and Public Health, University of Verona, Verona, Italy.
Ageing Lungs in European Cohorts (ALEC) study
University of Verona · ITImperial College London · GBUppsala University · SEEuropean University Cyprus · CYGerman Center for Lung Research · DEHaukeland University Hospital · NOReykjavík University · ISSwiss Tropical and Public Health Institute · CHTartu University Hospital · EEThe University of Melbourne · AUUniversitat Pompeu Fabra · ESUniversité Paris-Sud · FRUniversity of Antwerp · BEUniversity of Gothenburg · SEUniversity of Pavia · IT

Funding

Medical Research Council G0901214
6 · The paper itself

Abstract

Patients with concomitant features of asthma and chronic obstructive pulmonary disease (COPD) have a heavy disease burden.Using data collected prospectively in the European Community Respiratory Health Survey, we compared the risk factors, clinical history and lung function trajectories from early adulthood to late sixties of middle-aged subjects with asthma+COPD (n=179), past (n=263) or current (n=808) asthma alone, COPD alone (n=111) or none of these (n=3477).Interview data and pre-bronchodilator forced expiratory volume in 1 s (FEV

Indexed as

AsthmaPulmonary Disease, Chronic ObstructiveAdultAgedForced Expiratory VolumeHumansLungMiddle AgedRisk FactorsSpirometryVital CapacityYoung Adult

Identifiers

PMID33863744
PMCPMC8613837
OpenAlexW3156218510

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.