ArticleJournal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia2021
SARS-CoV-2-associated first episode of acute mania with psychotic features.
Article in Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Psychosis during the COVID-19 pandemic: A systematic review of case reports and case series.Journal of psychiatric research · 2022Pooled it
- COVID-19 and first manic episodes: a systematic review.Psychiatry research · 2022Pooled it
- COVID-19-associated psychosis: A systematic review of case reports.General hospital psychiatryPooled it
- Comparison of Antipsychotics in the Treatment of COVID-19-Induced First-Episode Psychosis: A Review of Case Studies.Cureus · 2026Review
- Acute and long-term effects of COVID-19 on brain and mental health: A narrative review.Brain, behavior, and immunity · 2025Review
- An Adolescent Presenting With Mania and Catatonia Associated With Coronavirus Disease-2019 Encephalitis.Cureus · 2024Article
- A rare clinical presentation after COVID-19: Manic episode with psychotic features.Psychiatry research case reports · 2023Article
- Mild Encephalitis/Encephalopathy with a Reversible Lesion in The Splenium.Noro psikiyatri arsivi · 2023Article
- First-episode mania after COVID-19: A case series in Iran.Frontiers in psychiatry · 2023Article
- Is SARS-CoV-2 a Risk Factor of Bipolar Disorder?-A Narrative Review.Journal of clinical medicine · 2022Review
- New variants and new symptoms in COVID-19: First episode psychosis and Cotard's Syndrome two months after infection with the B.1.1.7 variant of coronavirus.Schizophrenia research · 2022Article
- Clinical Aspects of Manic Episodes After SARS-CoV-2 Contagion or COVID-19.Frontiers in psychiatry · 2022Review
- A case of Sars-Cov-2-related mania with prominent psychosis>.Psychiatry research · 2021Article
- A novel adverse effect of the BNT162b2 mRNA vaccine: First episode of acute mania with psychotic features.Brain, behavior, & immunity - health · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite neuropsychiatric outcomes of SARS-CoV-2 infection are now under close scrutiny, psychoneuroimmunological characteristics of COVID-19 and precise pathophysiology of neuropsychiatric manifestations of the infection are still obscure. Moreover, there still exists a shortfall in demonstrating specific clinical manifestations of the brain involvement of the virus. Here, we presented a 33-year-old female patient with COVID-19, reporting acute-onset paranoid delusions symptoms, insomnia and irritability. Cranial MRI showed an hyperintense signal in the splenium of the corpus callosum with decreased apparent diffusion coefficient, which might possibly indicate the presence of cytotoxic edema related to the brain involvement of the infection. Following the completion of SARS-CoV-2 treatment, both cytotoxic edema and psychiatric symptoms resolved. In light of this report, we suggest that either heightened immune response and direct viral infection that SARS-CoV-2 may lead to such psychiatric manifestations and neuropsychiatric monitoring should be performed in patients with COVID-19. Prompt recognition of psychiatric consequences of COVID-19 may help clinicians provide guidance for differential diagnosis and manage them accordingly.
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Registered trials
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