Evidence map›Paper›PMID 33863485›Full record

ReviewImmunology and allergy clinics of North America2021

Genetics of Food Allergy.

Elisabet Johansson, Tesfaye B Mersha

Open access · greenAbstract readReview
In one paragraph

Review in Immunology and allergy clinics of North America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Zéro allergie research clinic: a clinical and research initiative in oral immunotherapy for managing IgE-mediated food allergy.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. A mutation inbioRxiv : the preprint server for biology · 2023
    Article
  12. Article
  13. Multi-omics profiling approach in food allergy.The World Allergy Organization journal · 2023
    Review
  14. Review
  15. Review
  16. Review
  17. Management of IgE-mediated food allergy in the 21st century.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2023
    Review
  18. Review
  19. Review
  20. Predictors and biomarkers of food allergy and sensitization in early childhood.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Elisabet JohanssonDivision of Asthma Research, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, 3333 Burnet Avenue, Cincinnati, OH 45229-3026, USA.
Tesfaye B MershaDivision of Asthma Research, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, 3333 Burnet Avenue, Cincinnati, OH 45229-3026, USA. Electronic address: tesfaye.mersha@cchmc.org.
University of Cincinnati · US

Funding

Unraveling ancestry and environmental exposure interactions in childhood asthmaR01HL132344 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI MERSHA, TESFAYE B. · 2016 to 2020
$3.4M
NHLBI NIH HHS R01 HL132344
6 · The paper itself

Abstract

The risk factors for food allergy (FA) include both genetic variants and environmental factors. Advances using both candidate-gene association studies and genome-wide approaches have led to the identification of FA-associated genes involved in immune responses and skin barrier functions. Epigenetic changes have also been associated with the risk of FA. In this chapter, we outline current understanding of the genetics, epigenetics and the interplay with environmental risk factors associated with FA. Future studies of gene-environment interactions, gene-gene interactions, and multi-omics integration may help shed light on the mechanisms of FA, and lead to improved diagnostic and treatment strategies.

Indexed as

Food HypersensitivityGenome-Wide Association StudyEpigenesis, GeneticFilaggrin ProteinsGene-Environment InteractionGenetic Predisposition to DiseaseHumansPolymorphism, Single NucleotideRisk FactorsFilaggrin ProteinsancestryepigeneticsfilaggrinFood allergygeneticsgenome-wide association study (GWAS)human leukocyte antigen complexsingle nucleotide polymorphism (SNP)

Identifiers

PMID33863485
PMCPMC8053212
OpenAlexW3141888760

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.