Evidence map›Paper›PMID 33863295›Full record

ArticleBMC public health2021

Factors associated with sexually transmitted infections among care-seeking adults in the African Cohort Study.

Michael Semwogerere, Nicole Dear, Joshua Tunnage, Domonique Reed, Hannah Kibuuka, Francis Kiweewa, Michael Iroezindu, Emmanuel Bahemana, Jonah Maswai, John Owuoth and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 3 countries.

Michael SemwogerereMakerere University Walter Reed Project, Kampala, Uganda.
Nicole DearU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Joshua TunnageU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Domonique ReedU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Hannah KibuukaMakerere University Walter Reed Project, Kampala, Uganda.
Francis KiweewaStrengthening Institutional Capacity for Research Administration (SICRA), Makerere University Lung Institute, Kampala, Uganda.
Michael IroezinduU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Emmanuel BahemanaU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Jonah MaswaiU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
John OwuothU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Trevor A CrowellU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Julie A AkeU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Christina S PolyakU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Allahna EsberU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA. aesber@hivresearch.org.
AFRICOS Study Group
Henry M. Jackson Foundation · USWalter Reed Army Institute of Research · USMakerere University Walter Reed Project · UGMakerere University · UGUnited States Army Medical Research Directorate - Africa · KE

Funding

PEPFAR
6 · The paper itself

Abstract

objectivesSexually transmitted infections (STIs) are a major cause of morbidity. Understanding drivers of transmission can inform effective prevention programs. We describe STI prevalence and identify factors associated with STIs in four African countries.

methodsThe African Cohort Study is an ongoing, prospective cohort in Kenya, Nigeria, Tanzania and Uganda. At enrollment, a physical exam was conducted and STI diagnosis made by a clinician using a syndromic management approach. Multivariable logistic regression was used to estimate adjusted odds ratios (aORs) and 95% confidence intervals (95% CIs) for factors associated with an STI diagnosis.

resultsAs of June 2020, 3544 participants were enrolled. STI prevalence was 7.7% and did not differ by HIV status (p = 0.30). Prevalence differed by syndrome (3.5% vaginal discharge, 1.5% genital ulcer, 2.1% lower abdominal pain, 0.2% inguinal bubo). The odds of having an STI were higher at all sites compared to Kisumu West, Kenya, and among those with a primary level education or below compared to those with secondary or higher (aOR: 1.77; 95% CI: 1.32-2.38). The odds of an STI diagnosis was higher among participants 18-29 years (aOR: 2.29; 95% CI: 1.35-3.87), females (aOR: 2.64; 95% CI: 1.94-3.59), and those with depression (aOR: 1.78; 95% CI: 1.32-2.38). Among PLWH, similar factors were independently associated with an STI diagnosis. Viral suppression was protective against STIs (aOR: 2.05; 95% CI: 1.32-3.20).

conclusionsPrevalence of STIs varied by site with young people and females most at risk for STIs. Mental health is a potential target area for intervention.

Indexed as

HIV InfectionsSexually Transmitted DiseasesAdolescentAdultCohort StudiesFemaleHumansKenyaNigeriaPrevalenceProspective StudiesTanzaniaUgandaPeople living with HIVSexually transmitted infectionsSub-Saharan Africa

Identifiers

PMID33863295
PMCPMC8052711
OpenAlexW3156812151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.