Evidence map›Paper›PMID 33862414›Full record

ArticleCancer epidemiology2021

Kidney cancer mortality disparities among Hispanics in the US.

Paulo S Pinheiro, Heidy N Medina, Karen E Callahan, Tulay Koru-Sengul, Janaki Sharma, Erin N Kobetz, Frank J Penedo

Open access · greenAbstract read
In one paragraph

Article in Cancer epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

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  13. Cancer mortality in Italian populations: differences between Italy and the USA.European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Paulo S PinheiroSylvester Comprehensive Cancer Center, University of Miami School of Medicine, USA; Public Health Sciences, University of Miami School of Medicine, USA. Electronic address: pxp464@med.miami.edu.
Heidy N MedinaPublic Health Sciences, University of Miami School of Medicine, USA. Electronic address: h.medina3@umiami.edu.
Karen E CallahanSchool of Public Health, University of Nevada Las Vegas, USA. Electronic address: karen.callahan@unlv.edu.
Tulay Koru-SengulSylvester Comprehensive Cancer Center, University of Miami School of Medicine, USA; Public Health Sciences, University of Miami School of Medicine, USA. Electronic address: tsengul@med.miami.edu.
Janaki SharmaSylvester Comprehensive Cancer Center, University of Miami School of Medicine, USA. Electronic address: jsharma@miami.edu.
Erin N KobetzSylvester Comprehensive Cancer Center, University of Miami School of Medicine, USA; Public Health Sciences, University of Miami School of Medicine, USA. Electronic address: ekobetz@med.miami.edu.
Frank J PenedoSylvester Comprehensive Cancer Center, University of Miami School of Medicine, USA; Department of Psychology, University of Miami, USA. Electronic address: fpenedo@miami.edu.
University of Miami · USUniversity of Nevada, Las Vegas · US

Funding

Tumor Biology Research ProgramP30CA240139 · NCI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Stephen D. Nimer · 2019 to 2026
$24.1M
NCI NIH HHS P30 CA240139
6 · The paper itself

Abstract

introductionKidney cancer incidence is increasing among Hispanics but rate differences by distinct group, such as Cuban, Puerto Rican, and Mexican have not been studied. To fill this knowledge gap, we use mortality data, reflecting fatal kidney cancers, to examine patterns by race-ethnicity, including detailed Hispanic groups, and correlate the mortality rates with each group's prevalence of known kidney cancer risk factors: smoking, obesity, hypertension, diabetes, and chronic kidney disease.

methodsWe used individual-level death data for California, Florida, and New York (2008-2018), and population prevalence data from the National Health Interview Surveys (2008-2018). Age-adjusted mortality rates (AAMRs) and regression-derived mortality rate ratios (MRRs) were computed. Pearson correlation analyses assessed the extent to which group-specific risk factor prevalence explained variability in observed AAMRs.

resultsUS-born Mexican Americans and American Indians had the highest rates and MRRs compared to Whites: 1.44 (95 %CI: 1.35-1.53) and 1.51 (1.38-1.64) for Mexican American men and women, respectively, and 1.54 (95 %CI: 1.25-1.89) and 1.53 (95 %CI: 1.15-2.04) for American Indians. In contrast, non-Mexican Hispanics had lower rates than Whites. Among males, positive correlations between AAMRs and smoking, obesity, and chronic kidney disease prevalence by race-ethnicity were found.

conclusionMexican Americans and American Indians are high-risk for fatal kidney cancer. Disparities are only partially attributable to higher smoking and obesity prevalence, and more so among men than women. A shared risk factor profile, as well as possible genetic similarities, may explain their disproportionately higher kidney cancer mortality, but further research is warranted.

Indexed as

Health Status DisparitiesAdolescentAdultAgedAged, 80 and overChildChild, PreschoolFemaleHispanic or LatinoHumansInfantInfant, NewbornKidney NeoplasmsMaleMiddle AgedRisk FactorsAmerican IndianCubanMexicanObesitySmoking

Identifiers

PMID33862414
PMCPMC8141025
OpenAlexW3155286849

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.