ArticlePLoS neglected tropical diseases2021
Short report: Introduction of chikungunya virus ECSA genotype into the Brazilian Midwest and its dispersion through the Americas.
Article in PLoS neglected tropical diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Primary infection with a Brazilian chikungunya virus isolate protects immunocompetent mice against detectable viremia following homologous rechallenge.Archives of virology · 2026Article
- Tracing the evolutionary and spatial dynamics of the 2022-2023 chikungunya outbreak in Paraguay and its regional spread across the Southern Cone.IJID regions · 2026Article
- Arbovirus diagnostics: from conventional methods to emerging technologies-a chikungunya virus-centric review.Frontiers in microbiology · 2026Review
- Article
- Revisiting the emergence of the Chikungunya virus in Alagoas, Northeast of Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- The High Capacity of BrazilianViruses · 2024Article
- Molecular characterization of Chikungunya virus recovered from patients in the Maranhão state, Brazil.Molecular biology reports · 2024Article
- The impact of anthropogenic climate change on pediatric viral diseases.Pediatric research · 2024Review
- High capacity of BrazilianbioRxiv : the preprint server for biology · 2023Article
- Rapid Epidemic Expansion of Chikungunya Virus East/Central/South African Lineage, Paraguay.Emerging infectious diseases · 2023Article
- Increased interregional virus exchange and nucleotide diversity outline the expansion of chikungunya virus in Brazil.Nature communications · 2023Article
- Review on Main Arboviruses Circulating on French Guiana, An Ultra-Peripheric European Region in South America.Viruses · 2023Review
- Rapid epidemic expansion of chikungunya virus-ECSA lineage in Paraguay.medRxiv : the preprint server for health sciences · 2023Article
- Chikungunya fever.Nature reviews. Disease primers · 2023Review
- Increased interregional virus exchange and nucleotide diversity outline the expansion of the chikungunya virus ECSA lineage in Brazil.medRxiv : the preprint server for health sciences · 2023Article
- Co-circulation ofFrontiers in microbiology · 2023Article
- Technology transfer during the COVID-19 pandemic: report on the first face-to-face practical training course in Brazil.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2023Article
- Clinical markers of post-Chikungunya chronic inflammatory joint disease: A Brazilian cohort.PLoS neglected tropical diseases · 2023Article
- Predictable Chikungunya Infection Dynamics in Brazil.Viruses · 2022Article
Corrections and comments
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Authors and funding
22 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since introduction into Brazil in 2014, chikungunya virus (CHIKV) has presented sustained transmission, although much is unknown about its circulation in the midwestern states. Here, we analyze 24 novel partial and near complete CHIKV genomes from Cuiaba, an urban metropolis located in the Brazilian midwestern state of Mato Grosso (MT). Nanopore technology was used for sequencing CHIKV complete genomes. Phylogenetic and epidemiological approaches were used to explore the recent spatio-temporal evolution and spread of the CHIKV-ECSA genotype in Midwest Brazil as well as in the Americas. Epidemiological data revealed a reduction in the number of reported cases over 2018-2020, likely as a consequence of a gradual accumulation of herd-immunity. Phylogeographic reconstructions revealed that at least two independent introductions of the ECSA lineage occurred in MT from a dispersion event originating in the northeastern region and suggest that the midwestern Brazilian region appears to have acted as a source of virus transmission towards Paraguay, a bordering South American country. Our results show a complex dynamic of transmission between epidemic seasons and suggest a possible role of Brazil as a source for international dispersion of the CHIKV-ECSA genotype to other countries in the Americas.
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