ArticlePLoS genetics2021
Tempo and mode in karyotype evolution revealed by a probabilistic model incorporating both chromosome number and morphology.
Article in PLoS genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed.
- Chromosomal rearrangements: tempo and mode of karyotype evolution in Scarabaeoidea.Journal of evolutionary biology · 2026Article
- The evolutionary genomics of meiotic drive.Molecular biology and evolution · 2026Article
- Polyommatine Blue Butterflies Reveal Unexpected Integrity of the W Sex Chromosome Amid Extensive Chromosomal Fragmentation Linked to Telomere Restoration.Genome biology and evolution · 2025Article
- Optimization of Chromosome Preparation and Karyotype Analysis of Winter Turnip Rape (International journal of molecular sciences · 2025Article
- Shifts in Chromosome Evolution Rates Shape the Karyotype Patterns of Leafcutting Ants.Ecology and evolution · 2024Article
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- Karyotyping of aneuploid and polyploid plants from low coverage whole-genome resequencing.BMC plant biology · 2023Article
- The Impact of Chromosomal Rearrangements in Speciation: From Micro- to Macroevolution.Cold Spring Harbor perspectives in biology · 2023Review
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- Chromosomal conservatism vs chromosomal megaevolution: enigma of karyotypic evolution in Lepidoptera.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2023Article
- Independent Evolution of Sex Chromosomes and Male Pregnancy-Related Genes in Two Seahorse Species.Molecular biology and evolution · 2023Article
- Ribosomal DNA Instability as a Potential Cause of Karyotype Evolution.Molecular biology and evolution · 2022Article
- Linkage mapping, comparative genome analysis, and QTL detection for growth in a non-model teleost, the meagre Argyrosomus regius, using ddRAD sequencing.Scientific reports · 2022Article
- The Evolution of Cytogenetic Traits inFrontiers in plant science · 2022Article
- Article
- Tempo and mode in karyotype evolution revealed by a probabilistic model incorporating both chromosome number and morphology.PLoS genetics · 2021Article
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2 authors.
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Abstract
Karyotype, including the chromosome and arm numbers, is a fundamental genetic characteristic of all organisms and has long been used as a species-diagnostic character. Additionally, karyotype evolution plays an important role in divergent adaptation and speciation. Centric fusion and fission change chromosome numbers, whereas the intra-chromosomal movement of the centromere, such as pericentric inversion, changes arm numbers. A probabilistic model simultaneously incorporating both chromosome and arm numbers has not been established. Here, we built a probabilistic model of karyotype evolution based on the "karyograph", which treats karyotype evolution as a walk on the two-dimensional space representing the chromosome and arm numbers. This model enables analysis of the stationary distribution with a stable karyotype for any given parameter. After evaluating their performance using simulated data, we applied our model to two large taxonomic groups of fish, Eurypterygii and series Otophysi, to perform maximum likelihood estimation of the transition rates and reconstruct the evolutionary history of karyotypes. The two taxa significantly differed in the evolution of arm number. The inclusion of speciation and extinction rates demonstrated possibly high extinction rates in species with karyotypes other than the most typical karyotype in both groups. Finally, we made a model including polyploidization rates and applied it to a small plant group. Thus, the use of this probabilistic model can contribute to a better understanding of tempo and mode in karyotype evolution and its possible role in speciation and extinction.
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