Evidence map›Paper›PMID 33861458›Full record

ReviewAdvances in experimental medicine and biology2021

Medicinal Species of the Genus Berberis: A Review of Their Traditional and Ethnomedicinal Uses, Phytochemistry and Pharmacology.

Zahra Sobhani, Maryam Akaberi, Mohammad Sadegh Amiri, Mahin Ramezani, Seyed Ahmad Emami, Amirhossein Sahebkar

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in experimental medicine and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Berberine Inhibits Dengue Virus through Dual Mechanisms.Molecules (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zahra SobhaniDepartment of Traditional Pharmacy, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Maryam AkaberiDepartment of Pharmacognosy, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammad Sadegh AmiriDepartment of Biology, Payame Noor University, Tehran, Iran.
Mahin RamezaniNanotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Seyed Ahmad EmamiDepartment of Traditional Pharmacy, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. emamia@mums.ac.ir.
Amirhossein SahebkarApplied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. sahebkara@mums.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Discovering new drugs for treating different health problems is one of the basic needs of human societies. There are various strategies to find new lead compounds. One of the most important strategies in this regard is using the knowledge in traditional and folk medicines as a valuable guide. Islamic traditional medicine (ITM) is a well reputed school of medicine with a long history. In the textbooks of this medical system, the properties and applications of many medicinal plants have been described. As a part of an ongoing project on plants used in ITM, in this study we investigated botany, traditional uses, phytochemistry, and pharmacology of Berberis spp. The great genus Berberis (Berberidaceae) consists of 594 species worldwide which have been used in different traditional medicines for a wide range of diseases. In ITM reference books such as Al-Hâwi fi'aṭ-Ṭibbe (Comprehensive Book of Medicine), Kâmel al-Sinâh aṭ-Ṭibbiyah (Complete Book of the Medical Art), Al-Qânun fi' aṭ-Ṭibbe (Canon of Medicine), Ḏakhireh Khârazmshâhi (Treasure of Khârazmshâh), and Makhzan al-Adwyah (Drug Treasure), different parts of B. vulgaris and B. integrimma, known as Zereshk, have been mainly prescribed for skin, liver, stomach, kidney, and eye problems. There are several pharmacological studies reporting beneficial effects of various Berberis plants confirming traditional uses. Most of the activities reported for Berberis is attributed to the presence of an important class of alkaloids namely isoquinolines. Nevertheless, clinical studies are necessary to confirm the therapeutic effects of different species of this genus.

Indexed as

BerberisPlants, MedicinalHumansMedicine, TraditionalPhytochemicalsPhytotherapyPlant ExtractsPhytochemicalsPlant ExtractsBarberryBerberidaceaeBerberineBerberis spp.Drug discoveryTraditional medicine

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.