ReviewAdvances in experimental medicine and biology2021
Ethnobotanical Uses, Phytochemistry and Pharmacology of Different Rheum Species (Polygonaceae): A Review.
Review in Advances in experimental medicine and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Constipation Mitigation by Rhubarb Extract in Middle-Aged Adults Is Linked to Gut Microbiome Modulation: A Double-Blind Randomized Placebo-Controlled Trial.International journal of molecular sciences · 2022Trial
- Learning from animals? shared plant use between Lua herders and water buffalo in Northern Thailand.Journal of ethnobiology and ethnomedicine · 2026Article
- Phytochemical Profiling, Anti-Inflammatory Action, and Human Gut Microbiota-Assisted Digestion ofNutrients · 2025Article
- The Hepatoprotective Properties of the Revised Formulation of Dahuang Xiaoshi Tang, an Ancient Chinese Herbal Decoction, Are Probed by Integrated Metabolomics and Network Pharmacology.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Insights into Biological and Ecological Features of Four Rare and Endemic Plants from the Northern Tian Shan (Kazakhstan).Plants (Basel, Switzerland) · 2025Article
- Isolation and Identification of Secondary Metabolites inMolecules (Basel, Switzerland) · 2025Article
- Renal Health Through Medicine-Food Homology: A Comprehensive Review of Botanical Micronutrients and Their Mechanisms.Nutrients · 2024Review
- The relationship between niche breadth and phylogenetic characteristics of eight species of rhubarb on the Qinghai-Tibet Plateau, Asia.Ecology and evolution · 2024Article
- Qualitative and quantitative analysis methods for quality control of rhubarb in Taiwan's markets.Frontiers in pharmacology · 2024Article
- The response of rhubarb to smut infection is revealed through a comparative transcriptome and metabolome study.Planta · 2023Article
- Molecular mechanism of Rhubarb in the treatment of non-small cell lung cancer based on network pharmacology and molecular docking technology.Molecular diversity · 2023Article
- Review on melanosis coli and anthraquinone-containing traditional Chinese herbs that cause melanosis coli.Frontiers in pharmacology · 2023Review
- Fecal fermentation characteristics of Rheum tanguticum polysaccharide and its effect on the modulation of gut microbial composition.Chinese medicine · 2022Article
- A Review on Rhubarb-Derived Substances as Modulators of Cardiovascular Risk Factors-A Special Emphasis on Anti-Obesity Action.Nutrients · 2022Review
- The Potential Roles of Unique Leaf Structure for the Adaptation ofPlants (Basel, Switzerland) · 2022Article
- Bacterial Inoculant and Sucrose Amendments Improve the Growth ofInternational journal of molecular sciences · 2022Article
- Comparison of Three Species of Rhubarb in Inhibiting Vascular Endothelial Injury via Regulation of PI3K/AKT/NF-Oxidative medicine and cellular longevity · 2022Article
- A Comparative Analysis of the Chloroplast Genomes of FourFrontiers in genetics · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Today, there is an increased tendency to use herbal remedies. Rhubarb refers to several species of the genus Rheum L. in the Polygonaceae family. This species-rich genus is mainly distributed in Asian countries. Several medicinal effects have been attributed to the Rheum spp. in the traditional and modern medicine such as healing lungs, liver, kidney, womb and bladder diseases, cancer, diabetes, insect bites, relapsing fevers, diarrhea and constipation. Various in vitro, in vivo and clinical studies have investigated the therapeutic effect of extracts, fractions and pure compounds isolated from different species of this genus. Considering the positive findings, several pharmaceutical formulations containing rhubarb extract like capsules, drops, mouthwashes and different topical formulations are now present in the market. However, there are other traditional therapeutic effects of rhubarb that have not been studied yet and it is of great importance to perform confirmatory experiments or clinical investigations. The current review summarizes general information regarding botany, phytochemistry, ethnobotany and pharmacological aspects of Rheum spp. It is hoped that the present review could motivate subsequent research on the other medicinal properties of these plants that have been neglected until today.
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