Evidence map›Paper›PMID 33861367›Full record

ReviewGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2021

Optical coherence tomography and the proximal lacrimal drainage system: a major review.

Mohammad Javed Ali, Swati Singh

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07571330 (Effectiveness of Upper Punctal Plug Occlusion in Patients With Dry Eye Disease With Previous Lower Punctal Occlusion.), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07571330 narecruitingnot on this mapstarted 2026, after this paper: background citation

Effectiveness of Upper Punctal Plug Occlusion in Patients With Dry Eye Disease With Previous Lower Punctal Occlusion.

TypeinterventionalSponsorUniversidad Autonoma de Nuevo LeonRan2026 to 2026Enrolled36ConditionsDED, Aqueous-deficient Dry Eye DiseaseArmsPunctal plug occlusion
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mohammad Javed AliGovindram Seksaria Institute of Dacryology, L.V. Prasad Eye Institute, Road No 2, Banjara Hills, Hyderabad, India. drjaved007@gmail.com.ORCID http://orcid.org/0000-0002-6363-9202
Swati SinghCenter for Ocular Regeneration, L.V. Prasad Eye Institute, Hyderabad, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo provide a major review of the literature on diagnostic and therapeutic implications, techniques, and utility of anterior segment optical coherence tomography (OCT) for the proximal lacrimal drainage system (PLDS).

methodsThe authors performed a PubMed search of articles published in the English language on anterior segment OCT for the proximal lacrimal drainage system. Data captured include evolution, techniques, diagnostic utility, therapeutic monitoring, outcomes, and limitations. Specific emphasis was laid on addressing the existing lacunae and the current practice patterns.

resultsThe PLDS parameters that can be studied by OCT include punctal shape and morphology, external and internal punctum diameters, punctum depth and area, intra-punctal tear meniscus, punctal reserve, punctum-canalicular junction, canalicular diameter at various depths, canalicular depth, canalicular cross-sectional area, canalicular volume, and fluid meniscus characteristics. Normative data is now available from across the globe. Several punctal and canalicular disorders show characteristic OCT features and have adjunctive value in diagnosis. Post-operative OCT imaging can help in monitoring the outcomes of selected surgical procedures and medical therapy. OCT studies have raised doubts about the previous beliefs of vertical canalicular height and the definition of punctal stenosis. OCT dacryography (OCTD) and 3-dimensional punctal and canalicular imaging are promising modalities to further explore the anatomy, physiology, and pathophysiology of the PLDS.

conclusionOptical coherence tomography techniques are increasingly playing a significant role in diagnosing and managing proximal lacrimal drainage disorders. Further improvements in imaging techniques, better resolution, standardized definitions, and measurements of punctal and canalicular parameters will expand its clinical usage and give impetus to minimally invasive lacrimal surgeries.

Indexed as

Lacrimal ApparatusLacrimal Apparatus DiseasesEyelidsHumansPostoperative PeriodTomography, Optical CoherenceCanaliculusImagingLacrimalOCTOptical coherence tomographyProximal lacrimal drainage systemPunctum

Identifiers

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.