Evidence map›Paper›PMID 33861144›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2021

SERCA2a-phospholamban interaction monitored by an interposed circularly permutated green fluorescent protein.

Maren E Arnold, Wolfgang R Dostmann, Jody Martin, Michael J Previs, Bradley Palmer, Martin LeWinter, Markus Meyer

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Maren E ArnoldDepartment of Medicine and Molecular Physiology and Biophysics, University of Vermont Larner College of Medicine, Burlington, Vermont.ORCID 0000-0002-2778-500X
Wolfgang R DostmannDepartment of Pharmacology, University of Vermont Larner College of Medicine, Burlington, Vermont.
Jody MartinDepartment of Pharmacology, School of Medicine, Cardiovascular Research Institute, University of California, Davis, California.
Michael J PrevisDepartment of Medicine and Molecular Physiology and Biophysics, University of Vermont Larner College of Medicine, Burlington, Vermont.
Bradley PalmerDepartment of Medicine and Molecular Physiology and Biophysics, University of Vermont Larner College of Medicine, Burlington, Vermont.
Martin LeWinterDepartment of Medicine and Molecular Physiology and Biophysics, University of Vermont Larner College of Medicine, Burlington, Vermont.ORCID 0000-0003-3938-3531
Markus MeyerDepartment of Medicine, Lillehei Heart Institute, University of Minnesota College of Medicine, Minneapolis, Minnesota.
University of Vermont · USUniversity of California, Davis · USUniversity of Minnesota · US

Funding

Sarcolemmal Calcium Extrusion Defect in Patients with Diastolic DysfunctionR01HL122744 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI LUSTGARTEN, DANIEL L, MEYER, MARKUS · 2015 to 2019
$1.9M
Molecular Modulation of Actomyosin Mechanics by Cardiac Myosin-Binding Protein CR00HL124041 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI PREVIS, MICHAEL JOSEPH · 2016 to 2018
$747k
HHS | National Institutes of Health (NIH) R01 HL-122744NHLBI NIH HHS R00 HL124041NHLBI NIH HHS R01 HL122744
6 · The paper itself

Abstract

The interaction of phospholamban (PLB) and the sarcoplasmic reticulum Ca

Indexed as

Myocardial ContractionAnimalsCalcium-Binding ProteinsCyclic AMP-Dependent Protein KinasesDNA, ComplementaryGreen Fluorescent ProteinsHEK293 CellsHumansMyocytes, CardiacPhospholambanRatsRecombinant Fusion ProteinsRecombinant ProteinsSarcoplasmic Reticulum Calcium-Transporting ATPasesTransfectionCalcium-Binding ProteinsCyclic AMP-Dependent Protein KinasesDNA, ComplementaryGreen Fluorescent ProteinsPhospholambanRecombinant Fusion ProteinsRecombinant ProteinsSarcoplasmic Reticulum Calcium-Transporting ATPasescalciumphospholambansarcoplasmic reticulumSERCA2a

Identifiers

PMID33861144
PMCPMC8289358
OpenAlexW3152810943

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.