Evidence map›Paper›PMID 33860848›Full record

ArticleJournal of cancer research and clinical oncology2022

The effect of surgery plus intensity-modulated radiotherapy on treatment in laryngeal cancer: A clinical retrospective study.

Kun Deng, Jingwei Yao, Shuqing Zeng, Meiling Wen, Jialu Huang, Tao Zhu, Shanyan Liu, Jianhong Zuo

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cancer research and clinical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Kun Deng *The Laboratory of Translational Medicine, Hengyang Medical School, University of South China, 28 Changsheng Road, Hengyang, 421001, Hunan, People's Republic of China.
Jingwei Yao *Nanhua Hospital of University of South China, Hengyang, 421002, Hunan, People's Republic of China.
Shuqing Zeng *The First Affiliated Hospital of University of South China, Hengyang, 421000, Hunan, People's Republic of China.
Meiling Wen *The First Affiliated Hospital of University of South China, Hengyang, 421000, Hunan, People's Republic of China.
Jialu HuangThe Laboratory of Translational Medicine, Hengyang Medical School, University of South China, 28 Changsheng Road, Hengyang, 421001, Hunan, People's Republic of China.
Tao ZhuThe First Affiliated Hospital of University of South China, Hengyang, 421000, Hunan, People's Republic of China.
Shanyan LiuNanhua Hospital of University of South China, Hengyang, 421002, Hunan, People's Republic of China.
Jianhong ZuoThe Laboratory of Translational Medicine, Hengyang Medical School, University of South China, 28 Changsheng Road, Hengyang, 421001, Hunan, People's Republic of China. 632138414@qq.com.ORCID http://orcid.org/0000-0002-6174-4850
First Affiliated Hospital of University of South China · CNUniversity of South China · CN

Funding

ey Research Program from the Science and Technology Department of Ningxia Hui Autonomous Region, China 2019BFH02012Key Research Program of Hunan Health Committee 20201909Program of Hengyang science and Technology Bureau 2017-1, 2020-67Program of Shaoyang science and Technology Bureau 2018FJ19
6 · The paper itself

Abstract

purposeAs a common head and neck tumor, laryngeal cancer has attracted heightened attention for its treatment and prognosis. Surgery and radiotherapy were mainly therapeutic approaches in laryngeal cancer, and intensity-modulated radiotherapy (IMRT) was a precision treatment way in radiotherapy. However, the therapeutic effect of surgery plus IMRT in laryngeal cancer was rarely reported. This study aims to determine the effect of IMRT on the treatment of patients with laryngeal cancer.

methodsA total of 125 patients with laryngeal cancer were collected and retrospectively analyzed based on their clinical data and follow-up results. These patients had a clear treatment plan for surgery and intensity-modulated radiotherapy.

resultsSmoking, lymph node metastasis, TNM staging and therapeutic approaches could affect the survival of patients with laryngeal cancer. It was shown that the laryngeal function retention rate in the simple IMRT group was significantly higher than the simple surgery group and surgery plus IMRT group. The 5-year survival rate of surgery plus IMRT, simple surgery and simple IMRT were 82.86%, 53.85% and 43.33%, respectively. The locoregional recurrences rate of surgery plus IMRT, simple surgery and simple IMRT were 14.29%, 34.62% and 43.33%.

conclusionSurgery plus IMRT was a feasible and efficacious treatment technique for patients with laryngeal cancer, which effectively prolong the survival time of patients.

Indexed as

CarcinomaLaryngeal NeoplasmsLaryngectomyRadiotherapy, Intensity-ModulatedAdultAgedAged, 80 and overChinaCombined Modality TherapyFemaleFollow-Up StudiesHumansLymphatic MetastasisMaleMiddle AgedNeoplasm Recurrence, LocalIntensity-modulated radiotherapyLaryngeal cancerPrognosisSurgeryTherapeutic effects

Identifiers

PMID33860848
PMCPMC11800924
OpenAlexW3156705141

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.