Evidence map›Paper›PMID 33860829›Full record

SynthesisEuropean radiology2021

Systematic review of research design and reporting of imaging studies applying convolutional neural networks for radiological cancer diagnosis.

Robert J O'Shea, Amy Rose Sharkey, Gary J R Cook, Vicky Goh

Abstract readSystematic Review
In one paragraph

Synthesis in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Robert J O'SheaCancer Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London, 5th floor, Becket House, 1 Lambeth Palace Road, London, SE1 7EU, UK. robert.1.oshea@kcl.ac.uk.ORCID http://orcid.org/0000-0003-4983-7912
Amy Rose SharkeyCancer Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London, 5th floor, Becket House, 1 Lambeth Palace Road, London, SE1 7EU, UK.
Gary J R CookCancer Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London, 5th floor, Becket House, 1 Lambeth Palace Road, London, SE1 7EU, UK.
Vicky GohCancer Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London, 5th floor, Becket House, 1 Lambeth Palace Road, London, SE1 7EU, UK.

Funding

Cancer Research UK 16463Wellcome Trust
6 · The paper itself

Abstract

objectivesTo perform a systematic review of design and reporting of imaging studies applying convolutional neural network models for radiological cancer diagnosis.

methodsA comprehensive search of PUBMED, EMBASE, MEDLINE and SCOPUS was performed for published studies applying convolutional neural network models to radiological cancer diagnosis from January 1, 2016, to August 1, 2020. Two independent reviewers measured compliance with the Checklist for Artificial Intelligence in Medical Imaging (CLAIM). Compliance was defined as the proportion of applicable CLAIM items satisfied.

resultsOne hundred eighty-six of 655 screened studies were included. Many studies did not meet the criteria for current design and reporting guidelines. Twenty-seven percent of studies documented eligibility criteria for their data (50/186, 95% CI 21-34%), 31% reported demographics for their study population (58/186, 95% CI 25-39%) and 49% of studies assessed model performance on test data partitions (91/186, 95% CI 42-57%). Median CLAIM compliance was 0.40 (IQR 0.33-0.49). Compliance correlated positively with publication year (ρ = 0.15, p = .04) and journal H-index (ρ = 0.27, p < .001). Clinical journals demonstrated higher mean compliance than technical journals (0.44 vs. 0.37, p < .001).

conclusionsOur findings highlight opportunities for improved design and reporting of convolutional neural network research for radiological cancer diagnosis. KEY POINTS: • Imaging studies applying convolutional neural networks (CNNs) for cancer diagnosis frequently omit key clinical information including eligibility criteria and population demographics. • Fewer than half of imaging studies assessed model performance on explicitly unobserved test data partitions. • Design and reporting standards have improved in CNN research for radiological cancer diagnosis, though many opportunities remain for further progress.

Indexed as

Artificial IntelligenceNeoplasmsDiagnostic ImagingHumansNeural Networks, ComputerResearch DesignArtificial intelligenceDeep learningDiagnosis, computer-assistedNeoplasmsResearch design

Identifiers

PMID33860829
PMCPMC8452579

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.