Evidence map›Paper›PMID 33860744›Full record

ArticlePublic health nutrition2021

Iron status in late pregnancy is inversely associated with birth weight in Colombia.

Alejandra Puerto, Annabelle Trojan, Nelson R Alvis-Zakzuk, Rossana López-Saleme, Francisco Edna-Estrada, Alvaro Alvarez, Nelson Alvis-Guzman, Josefina Zakzuk

Open access · bronzeAbstract read
In one paragraph

Article in Public health nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Iron deficiency with and without anemia in pregnancy: A scoping review of prevalence and perinatal impact.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Alejandra PuertoALZAK Foundation, Cartagena, Colombia.ORCID 0000-0001-5877-2001
Annabelle TrojanUniversidad de Cartagena, Carrera 5 #67-135, Edificio el Velero Apto 402, Barrio Crespo, Cartagena, Colombia.
Nelson R Alvis-ZakzukALZAK Foundation, Cartagena, Colombia.
Rossana López-SalemeUniversidad de Cartagena, Carrera 5 #67-135, Edificio el Velero Apto 402, Barrio Crespo, Cartagena, Colombia.
Francisco Edna-EstradaCentro de Investigación Para la Salud Materna Perinatal y de la Mujer, Clínica Maternidad Rafael Calvo C, Barranquilla, Colombia.
Alvaro AlvarezUniversidad de Cartagena, Carrera 5 #67-135, Edificio el Velero Apto 402, Barrio Crespo, Cartagena, Colombia.
Nelson Alvis-GuzmanALZAK Foundation, Cartagena, Colombia.
Josefina ZakzukALZAK Foundation, Cartagena, Colombia.ORCID 0000-0002-6007-5376
University of Cartagena · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveGestational anaemia (GA) is common in developing countries. This study assessed the relationship of late GA and negative perinatal outcomes in participants recruited in a reference maternity unit of the Caribbean region of Colombia.

designProspective analytical birth cohort study. Maternal Hb and serum ferritin (SF) levels were measured. GA was defined as Hb levels <6·82 mmol/l (<11 g/dl), SF depletion as SF levels <12 µg/l. Birth outcomes such as low birth weight (LBW), preterm birth (PB) and small for gestational age (SGA) were examined.

settingMothers in the first stage of labour, living in urban or rural areas of Bolívar, were enrolled in an obstetrical centre located in Cartagena, Colombia. Blood and stool samples were taken prior delivery. Maternal blood count, SF levels and infant anthropometric data were recorded for analysis.

participants1218 pregnant women aged 18-42 years and their newborns.

resultsPrevalence of GA and SF depletion was 41·6 % and 41·1 %, respectively. GA was positively associated with poverty-related sociodemographic conditions. Prenatal care attendance lowered the risk of PB, LBW and SGA. Birth weight was inversely associated with Hb levels, observing a -36·8 g decrease in newborn weight per 0·62 mmol/l (or 1 g/dl) of maternal Hb. SF depletion, but not anaemia, was associated with PB. SGA outcome showed a significant association with anaemia, but not a significant relationship with SF depletion.

conclusionsBirth weight and other-related perinatal outcomes are negatively associated with Hb and SF depletion. Prenatal care attendance reduced the risk of negative birth outcomes.

Indexed as

IronPremature BirthBirth WeightCohort StudiesColombiaFemaleHumansInfant, NewbornPregnancyPregnancy OutcomeProspective StudiesRisk FactorsIronAnaemiaBirth outcomesColombiaIron deficiencyIron statusLow birth weightPregnancy

Identifiers

PMID33860744
PMCPMC11082807
OpenAlexW3154522248

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.