ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2021
What might cervical vestibular-evoked myogenic potential abnormalities mean in essential tremor?
Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 7 citations in OpenAlex.
- Integrity of Brainstem Connections in Essential Tremor Using Auditory and Vestibular Evoked Potentials.Movement disorders clinical practice · 2026Article
- Cervical vestibular evoked myogenic potentials are not disturbed in hemifacial spasm and blepharospasm.Acta neurologica Belgica · 2025Article
- Exploring Heading Direction Perception in Cervical Dystonia, Tremor, and Their Coexistence.Brain sciences · 2024Article
- Vestibular reflexes in essential tremor: abnormalities of ocular and cervical vestibular-evoked myogenic potentials are associated with the cerebellum and brainstem involvement.Journal of neural transmission (Vienna, Austria : 1996) · 2023Article
- Initial Vestibular Function May Be Associated with Future Postural Instability in Parkinson's Disease.Journal of clinical medicine · 2022Article
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Authors and funding
4 authors at 2 institutions in 1 country.
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Abstract
AIM/
backgroundEssential tremor (ET) is one of the most common movement disorders. However, its pathogenesis is unclear. Human vestibular reflexes are essential not only for gait and posture but also for goal-directed voluntary movements. In this study, cervical vestibular-evoked myogenic potentials (cVEMPs), the electrophysiological equivalent of the vestibulo-collic reflex was studied in ET patients to understand the interaction between the tremor network and the vestibular neural pathways.
methodscVEMPs were recorded in 40 ET patients and 40 age and sex-matched healthy controls (HCs). The latencies of peaks p13 and n23 and peak-to-peak amplitude of p13-n23 were measured.
resultsThere was no statistically significant difference between the p13 latencies of the HC and ET groups (p 0.79 and p 0.23 for the right and left sides respectively). n23 latency was shortened bilaterally in the ET group (p 0.009 and p 0.02 for the right and left sides respectively). p13-n23 amplitudes of the ET patients were bilaterally reduced when compared with the HC (p <0.001 and p 0.001 for the right and left sides respectively).
conclusionInformation provided by vestibular afferents is crucial in the control of voluntary movements in humans. Despite this silent but significant effect, the role of the vestibular system in movement disorders is often overlooked. In this study, it was found that cVEMP responses reflecting the activity of the vestibulo-collic pathway were affected in ET which can be either caused by dysfunctional structures or pathways responsible from ET or an additional disorder of vestibular information processing in these patients.
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