Evidence map›Paper›PMID 33860384›Full record

ArticleHandbook of experimental pharmacology2021

Kv7 Channels and Excitability Disorders.

Frederick Jones, Nikita Gamper, Haixia Gao

Abstract read
PubMed Publisher
In one paragraph

Article in Handbook of experimental pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
15.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 37 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Phosphatidylinositol 4,5-bisphosphate activation mechanism of human KCNQ5.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Neuropathic pain; what we know and what we should do about it.Frontiers in pain research (Lausanne, Switzerland) · 2023
    Review
  16. Structural mechanisms for the activation of human cardiac KCNQ1 channel by electro-mechanical coupling enhancers.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  17. Article
  18. Clinically RelevantInternational journal of molecular sciences · 2022
    Article
  19. Evidence for Dual Activation ofInternational journal of molecular sciences · 2022
    Article
  20. Gain of function due to increased opening probability by twoProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Frederick JonesFaculty of Biological Sciences, University of Leeds, Leeds, UK.
Nikita GamperFaculty of Biological Sciences, University of Leeds, Leeds, UK. n.gamper@leeds.ac.uk.
Haixia GaoDepartment of Pharmacology, Hebei Medical University, Shijiazhuang, China. gaohx686@yahoo.com.
Hebei Medical University · CNUniversity of Leeds · GB

Funding

Wellcome Trust 212302/Z/18/Z
6 · The paper itself

Abstract

Kv7.1-Kv7.5 (KCNQ1-5) K

Indexed as

EpilepsyMental DisordersHumansKCNQ Potassium ChannelsNeuronsKCNQ Potassium ChannelsChannelopathyEpilepsyKCNQKv7 channelM currentPain

Identifiers

PMID33860384
OpenAlexW3153885388

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.