Evidence map›Paper›PMID 33860383›Full record

ArticleEuropean journal of applied physiology2021

Cerebral autoregulation assessed by near-infrared spectroscopy: validation using transcranial Doppler in patients with controlled hypertension, cognitive impairment and controls.

Arjen Mol, Carel G M Meskers, Marit L Sanders, Martin Müller, Andrea B Maier, Richard J A van Wezel, Jurgen A H R Claassen, Jan Willem J Elting

Registry-linked trialAbstract readMulticenter StudyValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of applied physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06133842 (CEReBral AutorEgulation in Non-cardiac SuRgery and Relationship to Postoperative DeliriUm State - CERBERUS Trial), which is not on this map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06133842 recruitingnot on this mapstarted 2024, after this paper: background citation

CEReBral AutorEgulation in Non-cardiac SuRgery and Relationship to Postoperative DeliriUm State - CERBERUS Trial

TypeobservationalSponsorBeth Israel Deaconess Medical CenterRan2024 to 2027Enrolled100ConditionsPerioperative/Postoperative Complications, Postoperative Cognitive Dysfunction, Postoperative Delirium, EEG With Periodic AbnormalitiesArmsIntra-op EEG and CO data collection
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. A systematic review, meta-analysisJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Dynamic cerebral autoregulation measured by diffuse correlation spectroscopy.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Article
  9. Transfer function analysis of dynamic cerebral autoregulation: A CARNet white paper 2022 update.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Review
  10. Article
  11. Article
  12. Correlation of Obesity and Overweight with Cervical Vascular Function Among Healthy Populations.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Arjen MolDepartment of Human Movement Sciences, @AgeAmsterdam, Amsterdam Movement Sciences, Vrije Universiteit Amsterdam, Van der Boechorstraat 9, 1081 BT, Amsterdam, The Netherlands. research@arjenmol.net.ORCID http://orcid.org/0000-0003-1588-7663
Carel G M MeskersDepartment of Rehabilitation Medicine, Amsterdam UMC, Vrije Universiteit, Amsterdam Movement Sciences, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0002-5056-5611
Marit L SandersDepartment of Geriatric Medicine, Radboud University Medical Center, Reinier Postlaan 4, 6525 GC, Nijmegen, The Netherlands.ORCID http://orcid.org/0000-0002-5512-5033
Martin MüllerDepartment of Neurology, Lucerne Kantonsspital, Spitalstrasse, CH-6000, Lucerne, Switzerland.ORCID http://orcid.org/0000-0002-0041-9296
Andrea B MaierDepartment of Human Movement Sciences, @AgeAmsterdam, Amsterdam Movement Sciences, Vrije Universiteit Amsterdam, Van der Boechorstraat 9, 1081 BT, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0001-7206-1724
Richard J A van WezelDepartment of Biophysics, Donders Institute for Brain, Cognition and Behaviour, Radboud University, Heijendaalseweg 135, 6525 AJ, Nijmegen, The Netherlands.ORCID http://orcid.org/0000-0001-5753-7069
Jurgen A H R ClaassenDepartment of Geriatric Medicine, Radboud University Medical Center, Reinier Postlaan 4, 6525 GC, Nijmegen, The Netherlands.ORCID http://orcid.org/0000-0002-1778-8151
Jan Willem J EltingDepartment of Neurology, University Medical Center Groningen, Hanzeplein 1, 9713GZ, Groningen, The Netherlands.ORCID http://orcid.org/0000-0003-3991-7097

Funding

Stichting voor de Technische Wetenschappen 14901
6 · The paper itself

Abstract

purposeCerebral autoregulation (CA) aims to attenuate the effects of blood pressure variation on cerebral blood flow. This study assessed the criterion validity of CA derived from near-infrared spectroscopy (NIRS) as an alternative for Transcranial Doppler (TCD).

methodsMeasurements of continuous blood pressure (BP), oxygenated hemoglobin (O

resultsNIRS- and TCD-derived CA estimates were significantly correlated during supine rest (ρ = 0.22-0.30, N = 111-120) and repeated sit-to-stand transitions (ρ = 0.46-0.61, N = 19-32). BAloa separation ranged between 87° and 112° (supine rest) and 65°-77° (repeated sit to stand transitions).

conclusionCriterion validity of NIRS-derived CA measures allows for comparison between groups but was insufficient for clinical application in individuals.

Indexed as

Spectroscopy, Near-InfraredUltrasonography, Doppler, TranscranialAgedAged, 80 and overBlood Flow VelocityCase-Control StudiesCerebrovascular CirculationCognitive DysfunctionFemaleHomeostasisHumansHypertensionMaleMiddle AgedCerebral autoregulationCognitive dysfunctionHypertensionNear-infrared spectroscopyTranscranial Doppler

Identifiers

PMID33860383
PMCPMC8260523

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.