ArticleAnnals of gastroenterological surgery2021
Risk of emergency surgery for complicated appendicitis: Japanese nationwide study.
Article in Annals of gastroenterological surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 26 citations in OpenAlex.
- Treatment of uncomplicated appendicitis: is interval appendectomy an effective strategy?Surgery today · 2026Article
- Association between preoperative neutrophil-to-lymphocyte ratio and length of stay in pediatric patients undergoing laparoscopic appendectomy: a retrospective cohort study.BMC pediatrics · 2025Article
- Clinical outcomes and optimal indications for nonoperative management of acute appendicitis in adult patients: a comprehensive literature review.Annals of coloproctology · 2025Review
- Surgical outcomes of emergency open appendectomy for acute appendicitis: an audit of 2268 patients in a single center.Nagoya journal of medical science · 2025Article
- The benefits of interval appendectomy and risk factors for nonoperative management failure in the therapeutic strategy for complicated appendicitis.Surgery today · 2024Article
- A case of acute appendicitis caused by obstruction due to caecal cancer.Journal of surgical case reports · 2024Article
- The Value of Complete Blood Count Parameters in Predicting Complicated Acute Appendicitis; a Prognostic Accuracy Study.Archives of academic emergency medicine · 2023Article
- Review
- The impact of bloodstream infection in patients undergoing appendectomy due to acute appendicitis.Surgery in practice and science · 2022Article
- Laparoscopic Surgery for Acute Diffuse Peritonitis Due to Gastrointestinal Perforation: A Nationwide Epidemiologic Study Using the National Clinical Database.Annals of gastroenterological surgery · 2022Article
- Patient backgrounds and short-term outcomes of complicated appendicitis differ from those of uncomplicated appendicitis.Annals of gastroenterological surgery · 2022Article
- Risk of emergency surgery for complicated appendicitis: Japanese nationwide study.Annals of gastroenterological surgery · 2021Article
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Authors and funding
14 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimAppendicitis is divided into two categories: complicated appendicitis (CA) and uncomplicated appendicitis (UA). In pediatric patients with CA, the use of interval appendectomy (IA), which is non-operative management followed by elective surgery, has decreased the number of postoperative complications. Before discussing the merit of IA for adult patients, we need to clarify whether the frequency and seriousness of the complication rate after emergency surgery is higher for CA than for UA.
methodsThis retrospective cohort study included adult patients who underwent appendectomy and who were registered in the National Clinical Database (NCD) from 2014 to 2016. Patients with CA who underwent emergency appendectomy comprised the CA group. Patients with UA comprised the UA group. Patients with chronic or recurrent appendicitis who underwent elective appendectomy comprised the elective appendectomy (EA) group. Primary outcomes were all morbidity, serious morbidity, and mortality within 30 days after appendectomy.
resultsWe included 109 256 patients in the study: 14 798 CA, 86 876 UA, and 7582 EA patients. Compared with the UA group, the rates of all morbidity, serious morbidity, and mortality were significantly higher in the CA group. All morbidity, serious morbidity, and mortality rates were significantly lower in the EA group than in the other two groups.
conclusionsWe confirmed that emergency surgery for CA places the patient at relatively higher risk. We also showed that the risk associated with EA is significantly lower than that for the other methods.
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