Evidence map›Paper›PMID 33860001›Full record

ReviewFrontiers in cardiovascular medicine2021

Radiation-Induced Vascular Disease-A State-of-the-Art Review.

Eric H Yang, Konstantinos Marmagkiolis, Dinu V Balanescu, Abdul Hakeem, Teodora Donisan, William Finch, Renu Virmani, Joerg Herrman, Mehmet Cilingiroglu, Cindy L Grines and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 2 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 2 syntheses or guidelines pooled it, 80 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Coronary Perforation During Excimer Laser Angioplasty in a Patient With Prior Thoracic Radiotherapy.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Article
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  10. Aortic response to cancer therapy: a narrative review of the radiotherapy paradox and clinical implications.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 2 countries.

Eric H YangCardio-Oncology Program, Division of Cardiology, Department of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.
Konstantinos MarmagkiolisHospital Corporation of America Northside Hospital, St. Petersburg, FL, United States.
Dinu V BalanescuDepartment of Internal Medicine, Beaumont Hospital, Royal Oak, MI, United States.
Abdul HakeemDivision of Cardiovascular Diseases & Hypertension, Robert Wood Johnson Medical School, New Brunswick, NJ, United States.
Teodora DonisanDepartment of Internal Medicine, Beaumont Hospital, Royal Oak, MI, United States.
William FinchCardio-Oncology Program, Division of Cardiology, Department of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.
Renu VirmaniCVPath Institute, Gaithersburg, MD, United States.
Joerg HerrmanDivision of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, United States.
Mehmet CilingirogluDepartment of Cardiology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Cindy L GrinesCardiovascular Institute, Northside Hospital, Atlanta, GA, United States.
Konstantinos ToutouzasAthens Medical School, Hippokration General Hospital, Athens, Greece.
Cezar IliescuDepartment of Cardiology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Beaumont Hospital, Royal Oak · USNorthside Hospital · USUniversity of California, Los Angeles · USCVPath Institute · USHippocration General Hospital · GRJohnson University · USMayo Clinic in Arizona · USThe University of Texas MD Anderson Cancer Center · USUniversity of Hawaiʻi at Mānoa · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the 1990s, there has been a steady increase in the number of cancer survivors to an estimated 17 million in 2019 in the US alone. Radiation therapy today is applied to a variety of malignancies and over 50% of cancer patients. The effects of ionizing radiation on cardiac structure and function, so-called radiation-induced heart disease (RIHD), have been extensively studied. We review the available published data on the mechanisms and manifestations of RIHD, with a focus on vascular disease, as well as proposed strategies for its prevention, screening, diagnosis, and management.

Indexed as

cancercardio-oncologycoronary artery diseaseperipheral arterial diseaseradiation therapy

Identifiers

PMID33860001
PMCPMC8042773
OpenAlexW3146005342

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.