Evidence map›Paper›PMID 33859865›Full record

ArticleKDD : proceedings. International Conference on Knowledge Discovery & Data Mining2019

MetaPred: Meta-Learning for Clinical Risk Prediction with Limited Patient Electronic Health Records.

Xi Sheryl Zhang, Fengyi Tang, Hiroko H Dodge, Jiayu Zhou, Fei Wang

Abstract read
In one paragraph

Article in KDD : proceedings. International Conference on Knowledge Discovery & Data Mining, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
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  13. Meta-Learning on Augmented Gene Expression Profiles for Enhanced Lung Cancer Detection.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2024
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  16. Clinical Risk Prediction Models with Meta-Learning Prototypes of Patient Heterogeneity.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2023
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  20. Improving suicide risk prediction via targeted data fusion: proof of concept using medical claims data.Journal of the American Medical Informatics Association : JAMIA · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xi Sheryl ZhangDepartment of Healthcare Policy and Research. Weill Cornell Medicine. Cornell University.
Fengyi TangDepartment of Computer Science and Engineering. Michigan State University.
Hiroko H DodgeMichigan Alzheimer's Disease Center, Department of Neurology, University of Michigan.
Jiayu ZhouDepartment of Computer Science and Engineering. Michigan State University.
Fei WangDepartment of Healthcare Policy and Research. Weill Cornell Medicine. Cornell University.

Funding

Research Education ComponentP30AG066518 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI KEVIN M DUFF, Lisa C Silbert · 2020 to 2026
$28.6M
Outreach, Recruitment and Education CoreP30AG008017 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI DODGE, HIROKO HAYAMA · 1990 to 2019
$27.7M
Michigan Alzheimer's Disease Core CenterP30AG053760 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIEBERMAN, ANDREW P · 2016 to 2020
$10.1M
Conversational Engagement as a Means to Delay Onset AD: Phase II Administrative SupplementR01AG051628 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI DODGE, HIROKO HAYAMA · 2016 to 2020
$4.8M
Web-enabled social interaction to delay cognitive decline among seniors with MCI: Phase I Administrative SupplementR01AG056102 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI DODGE, HIROKO HAYAMA · 2017 to 2021
$4.6M
NIA NIH HHS P30 AG008017NIA NIH HHS P30 AG053760NIA NIH HHS P30 AG066518NIA NIH HHS R01 AG051628NIA NIH HHS R01 AG056102
6 · The paper itself

Abstract

In recent years, large amounts of health data, such as patient Electronic Health Records (EHR), are becoming readily available. This provides an unprecedented opportunity for knowledge discovery and data mining algorithms to dig insights from them, which can, later on, be helpful to the improvement of the quality of care delivery. Predictive modeling of clinical risks, including in-hospital mortality, hospital readmission, chronic disease onset, condition exacerbation, etc., from patient EHR, is one of the health data analytic problems that attract lots of the interests. The reason is not only because the problem is important in clinical settings, but also is challenging when working with EHR such as sparsity, irregularity, temporality, etc. Different from applications in other domains such as computer vision and natural language processing, the data samples in medicine (patients) are relatively limited, which creates lots of troubles for building effective predictive models, especially for complicated ones such as deep learning. In this paper, we propose MetaPred, a meta-learning framework for clinical risk prediction from longitudinal patient EHR. In particular, in order to predict the target risk with limited data samples, we train a meta-learner from a set of related risk prediction tasks which learns how a good predictor is trained. The meta-learned can then be directly used in target risk prediction, and the limited available samples in the target domain can be used for further fine-tuning the model performance. The effectiveness of MetaPred is tested on a real patient EHR repository from Oregon Health & Science University. We are able to demonstrate that with Convolutional Neural Network (CNN) and Recurrent Neural Network (RNN) as base predictors, MetaPred can achieve much better performance for predicting target risk with low resources comparing with the predictor trained on the limited samples available for this risk alone.

Indexed as

clinical risk predictionelectronic health recordsmeta-learning

Identifiers

PMID33859865
PMCPMC8046258

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.