Evidence map›Paper›PMID 33859795›Full record

ArticleACS medicinal chemistry letters2021

Discovery of 2,4-1

Johan J N Veerman, Yorik B Bruseker, Eddy Damen, Erik H Heijne, Wendy van Bruggen, Koen F W Hekking, Rob Winkel, Christopher D Hupp, Anthony D Keefe, Julie Liu and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS medicinal chemistry letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Building Block-Centric Approach to DNA-Encoded Library Design.Journal of chemical information and modeling · 2024
    Article
  2. Review
  3. Small-molecule discovery through DNA-encoded libraries.Nature reviews. Drug discovery · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Johan J N VeermanZoBio BV, J.H. Oortweg 19, 2333 CH Leiden, The Netherlands.
Yorik B BrusekerMercachem BV, Department of Medicinal Chemistry, Kerkenbos 1013, 6546 BB Nijmegen, The Netherlands.
Eddy DamenMercachem BV, Department of Medicinal Chemistry, Kerkenbos 1013, 6546 BB Nijmegen, The Netherlands.
Erik H HeijneMercachem BV, Department of Medicinal Chemistry, Kerkenbos 1013, 6546 BB Nijmegen, The Netherlands.
Wendy van BruggenMercachem BV, Department of Medicinal Chemistry, Kerkenbos 1013, 6546 BB Nijmegen, The Netherlands.
Koen F W HekkingMercachem BV, Department of Medicinal Chemistry, Kerkenbos 1013, 6546 BB Nijmegen, The Netherlands.
Rob WinkelMercachem BV, Department of Medicinal Chemistry, Kerkenbos 1013, 6546 BB Nijmegen, The Netherlands.
Christopher D HuppX-Chem, Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States.
Anthony D KeefeX-Chem, Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States.
Julie LiuCivetta Therapeutics, 10 Wilson Road, Cambridge, Massachusetts 02138, United States.
Heather A ThomsonX-Chem, Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States.
Ying ZhangX-Chem, Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States.
John W CuozzoX-Chem, Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States.
Andrew J McRinerX-Chem, Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States.
Mark J MulvihillHiberCell Inc., New York, New York 10019, United States.
Peter van RijnsbergenMercachem BV, Department of Medicinal Chemistry, Kerkenbos 1013, 6546 BB Nijmegen, The Netherlands.
Birgit ZechAnavoTherapeutics BV, J.H. Oortweg 19, 2333 CH Leiden, The Netherlands.
Louis M RenzettiBridge Medicines LLC, New York, New York 10017, United States.
Lee BabissWilmington, North Carolina 28405, United States.
Gerhard MüllerAnavoTherapeutics BV, J.H. Oortweg 19, 2333 CH Leiden, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein we report the discovery of 2,4-1

Identifiers

PMID33859795
PMCPMC8040042

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.