Evidence map›Paper›PMID 33859773›Full record

ArticleECS transactions2017

Carbon Nanotube-Based Microelectrodes for Enhanced Neurochemical Detection.

A G Zestos, B J Venton

Open access · greenAbstract read
In one paragraph

Article in ECS transactions, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

A G ZestosDepartment of Chemistry, American University, Washington, D.C., 20016, USA.
B J VentonDepartment of Chemistry, University of Virginia, Charlottesville, VA 22903, USA.
American University · USUniversity of Virginia · US

Funding

Carbon nanotube fiber and yarn microelectrodes for high temporal resolution measuR21DA037584 · NIDA · UNIVERSITY OF VIRGINIA · PI VENTON, B. JILL · 2014 to 2015
$413k
NIDA NIH HHS R21 DA037584
6 · The paper itself

Abstract

Carbon nanotube (CNT) fiber microelectrodes have been developed as electrode materials for the detection of neurotransmitters using fast scan cyclic voltammetry (FSCV). We have used acid-wet spinning to create "neat" carbon nanotube fibers and utilized them as electrode materials. Thirty-forty micron diameter acid spun CNT fiber microelectrodes were more sensitive than PEI-CNT fiber microelectrodes, with a 3 nM limit of detection. They also had faster electron transfer kinetics and a greater reversibility for the oxidation of dopamine using FSCV than CFMEs and other carbon nanomaterials. The acid spun CNT fiber microelectrodes also displayed a frequency independent response for the peak oxidation current of dopamine. This property was also seen in other CNT materials such as PEI-CNT fiber microelectrodes and CNT-Yarn microelectrodes. Upon varying the frequency from 10 Hz to 100 Hz, there was no decrease in sensitivity. When scanning at 2,000 V/s, there was no decrease in sensitivity upon changing the frequency from 10 Hz to 500 Hz. This could potentially allow for a 2 ms sampling rate for FSCV, comparable to those used with amperometry as opposed to 100 ms temporal resolution of traditional FSCV, an almost two orders of magnitude difference. Since the frequency independent response is seen with many CNT fibers/yarns, it suggests it is a fundamental property of the CNTs shared by many types of CNT fibers and yarns.

Identifiers

PMID33859773
PMCPMC8046031
OpenAlexW2727107414

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.