Evidence map›Paper›PMID 33859762›Full record

ArticleTheranostics2021

The combined induction of liver progenitor cells and the suppression of stellate cells by small molecules reverts chronic hepatic dysfunction.

Wei-Jian Huang, Xu Zhou, Gong-Bo Fu, Min Ding, Hong-Ping Wu, Min Zeng, Hong-Dan Zhang, Ling-Yan Xu, Yi Gao, Hong-Yang Wang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Periplakin Attenuates Liver Fibrosis via Reprogramming CD44Cellular and molecular gastroenterology and hepatology · 2025
    Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. CD24Cell & bioscience · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Wei-Jian HuangInternational Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.
Xu ZhouInternational Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.
Gong-Bo FuInternational Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.
Min DingDepartment of Interventional Oncology, Renji Hospital, Jiaotong University School of Medicine, Shanghai, China.
Hong-Ping WuInternational Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.
Min ZengInternational Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.
Hong-Dan ZhangShanghai Celliver Biotechnology Co. Ltd., Shanghai, China.
Ling-Yan XuDepartment of Pharmacy, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, East Campus, Shanghai, China.
Yi GaoDepartment of Hepatobiliary Surgery II, Guangdong Provincial Research Center for Artificial Organ and Tissue Engineering, Zhujiang Hospital, Southern Medical University.
Hong-Yang WangInternational Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.
He-Xin YanInternational Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AmidesAnimalsCarbon TetrachlorideCD24 AntigenCells, CulturedGene ExpressionHepatic Stellate CellsHepatocytesHumansLiverLiver CirrhosisLiver RegenerationMaleMiceMice, Inbred C57BLPyridinesAmidesCarbon TetrachlorideCD24 AntigenChir 99021PyridinesPyrimidinesSmall Molecule LibrariesY 27632in vivo reprogramingliver fibrosisliver progenitor cellssmall moleculesstellate cells

Identifiers

PMID33859762
PMCPMC8039967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.