Evidence map›Paper›PMID 33859749›Full record

ArticleTheranostics2021

Deep-learning and MR images to target hypoxic habitats with evofosfamide in preclinical models of sarcoma.

Bruna V Jardim-Perassi, Wei Mu, Suning Huang, Michal R Tomaszewski, Jan Poleszczuk, Mahmoud A Abdalah, Mikalai M Budzevich, William Dominguez-Viqueira, Damon R Reed, Marilyn M Bui and 3 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Bruna V Jardim-PerassiDepartment of Cancer Physiology, Moffitt Cancer Center, Tampa, US.
Wei MuDepartment of Cancer Physiology, Moffitt Cancer Center, Tampa, US.
Suning HuangDepartment of Cancer Physiology, Moffitt Cancer Center, Tampa, US.
Michal R TomaszewskiDepartment of Cancer Physiology, Moffitt Cancer Center, Tampa, US.
Jan PoleszczukDepartment of Integrated Mathematical Oncology, Moffitt Cancer Center, Tampa, US.
Mahmoud A AbdalahQuantitative Imaging Core, Moffitt Cancer Center, Tampa, Florida.
Mikalai M BudzevichSmall Animal Imaging Laboratory, Moffitt Cancer Center, Tampa, Florida.
William Dominguez-ViqueiraSmall Animal Imaging Laboratory, Moffitt Cancer Center, Tampa, Florida.
Damon R ReedDepartment of Interdisciplinary Cancer Management, Adolescent and Young Adult Program, Moffitt Cancer Center, Tampa, Florida.
Marilyn M BuiDepartment of Pathology, Moffitt Cancer Center, Tampa, Florida.
Joseph O JohnsonAnalytic Microscopy Core, Moffitt Cancer Center, Tampa, Florida.
Gary V MartinezDepartment of Cancer Physiology, Moffitt Cancer Center, Tampa, US.
Robert J GilliesDepartment of Cancer Physiology, Moffitt Cancer Center, Tampa, US.
Moffitt Cancer Center · US

Funding

TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI John L. Cleveland · 1998 to 2026
$93.5M
Imaging Habitats in SarcomaR01CA187532 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI GILLIES, ROBERT J., MARTINEZ, GARY · 2015 to 2019
$2.7M
NCI NIH HHS P30 CA076292NCI NIH HHS R01 CA187532
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsArtificial IntelligenceCell Line, TumorDeep LearningDisease Models, AnimalDoxorubicinEcosystemFemaleHumansHypoxiaMagnetic Resonance ImagingMiceMice, Inbred C3HMice, SCIDNitroimidazolesPhosphoramide MustardsDoxorubicinNitroimidazolesPhosphoramide MustardsProdrugsTH 302deep learninghypoxiahypoxia-activated prodrugsin-vivo imagingtumor microenvironment

Identifiers

PMID33859749
PMCPMC8039958
OpenAlexW3136519583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.