Evidence map›Paper›PMID 33859710›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2021

Thymoquinone Ameliorates Lung Inflammation and Pathological Changes Observed in Lipopolysaccharide-Induced Lung Injury.

Mostafa Boskabady, Mohammad Reza Khazdair, Rahimeh Bargi, Saeideh Saadat, Arghavan Memarzia, Nema Mohammadian Roshan, Mahmoud Hosseini, Vahid Reza Askari, Mohammad Hossein Boskabady

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Protective effects ofVeterinary research forum : an international quarterly journal · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Molecules (Basel, Switzerland) · 2022
    Review
  11. Article
  12. Article
  13. Protective Effects of Thymoquinone, an Active Compound ofMolecules (Basel, Switzerland) · 2021
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Mostafa BoskabadyApplied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammad Reza KhazdairCardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran.ORCID https://orcid.org/0000-0001-9854-6121
Rahimeh BargiDepartment of Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Saeideh SaadatDepartment of Physiology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.ORCID https://orcid.org/0000-0001-8588-7365
Arghavan MemarziaDepartment of Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Nema Mohammadian RoshanDepartment of Pathology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mahmoud HosseiniApplied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID https://orcid.org/0000-0001-6425-5123
Vahid Reza AskariApplied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID https://orcid.org/0000-0001-9268-6270
Mohammad Hossein BoskabadyApplied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID https://orcid.org/0000-0001-5736-9755
Mashhad University of Medical Sciences · IRBirjand University of Medical Sciences · IRZahedan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-inflammatory, antioxidant, and immunomodulatory effects of thymoquinone (TQ) have been shown. The effects of TQ on lipopolysaccharide- (LPS-) induced inflammation and pathological changes in rats' lung were investigated in this study. Four groups of rats included (1) control (saline treated); (2) LPS (treated with 1 mg/kg/day i.p. for two weeks); and (3 and 4) 5 or 10 mg/kg TQ i.p. 30 min prior to LPS administration. Total and differential WBC counts in the blood and bronchoalveolar fluid (BALF), TGF-

Identifiers

PMID33859710
PMCPMC8024078
OpenAlexW3150739026

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.